抗菌药物的治疗药物监测
Therapeutic drug monitoring of antimicrobials.
作者信息
Balakrishnan Indran, Shorten Robert J
机构信息
Department of Medical Microbiology, Royal Free London NHS Foundation Trust, London, UK Centre for Clinical Microbiology, University College London, Royal Free Campus, London, UK.
Centre for Clinical Microbiology, University College London, Royal Free Campus, London, UK Public Health Laboratory Manchester, Manchester Royal Infirmary, Manchester, UK
出版信息
Ann Clin Biochem. 2016 May;53(Pt 3):333-46. doi: 10.1177/0004563215618981. Epub 2015 Nov 10.
As pathology services become more centralized and automated, the measurement of therapeutic antimicrobial drugs concentrations is increasingly performed in clinical biochemistry or 'blood science' laboratories. This review outlines key groups of antimicrobial agents: aminoglycosides, glycopeptides, antifungal agents and antituberculosis agents, their role in managing infectious diseases, and the reasons why serum concentration measurement is important.
随着病理服务变得更加集中化和自动化，治疗性抗菌药物浓度的测定越来越多地在临床生物化学或“血液科学”实验室中进行。本综述概述了抗菌药物的主要类别：氨基糖苷类、糖肽类、抗真菌药物和抗结核药物，它们在管理传染病中的作用，以及测定血清浓度重要性的原因。
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