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膝关节或髋关节置换术与止痛注射的医疗保健利用情况及成本

Healthcare Utilization and Costs of Knee or Hip Replacements versus Pain-Relief Injections.

作者信息

Pasquale Margaret K, Louder Anthony M, Cheung Raymond Y, Reiners Andrew T, Mardekian Jack, Sanchez Robert J, Goli Veerainder

机构信息

Dr Pasquale is Research Manager, Comprehensive Health Insights, Humana, Louisville, KY.

Dr Louder is Principal Researcher, Comprehensive Health Insights, Humana, Louisville, KY.

出版信息

Am Health Drug Benefits. 2015 Oct;8(7):384-94.

Abstract

BACKGROUND

Given the dramatic increase in total knee and hip replacement procedures among the US population aged 45 years and older, there is a need to compare the downstream healthcare utilization and costs between patients who undergo joint replacement and those who receive intraarticular injections as a low-cost alternative.

OBJECTIVE

To compare changes in osteoarthritis (OA)-related healthcare utilization and costs for Medicare members with OA who underwent knee or hip replacement versus those receiving steroid or viscosupplementation injections.

METHODS

Medicare members aged ≥45 years diagnosed with OA were identified for this retrospective longitudinal study. Data were compared for patients who underwent primary knee or hip replacement surgery between July 1, 2007, and June 30, 2012, and those receiving injection of pain-relief medication during the same period. The date of joint replacement surgery was considered the index date. For the comparison cohort, the index date was 180 days postinjection of the first intraarticular injection. Medical and pharmacy claims were examined longitudinally in 90-day increments, from 180 days preindex until 360 days postindex. Difference-in-difference analyses were conducted to compare the change in OA-related healthcare costs, postindex versus preindex, between the study cohorts. Time-to-event analyses were used to measure rates of readmissions and venous thromboembolism (VTE).

RESULTS

The mean age was 70.7 years for patients with knee replacement, 71.7 years for those with hip replacement, and 71.1 years for those receiving pain-relief injection (P <.0001). The RxRisk-V comorbidity index scores were 4.7, 4.4, and 4.8, respectively (P <.0001). Difference-in-difference analyses indicated that decreases in OA-related costs were greater for the joint replacement cohorts (coefficient for knee replacementtime: -0.603; hip replacementtime: -0.438; P <.001 for both) than for the comparison cohort. The VTE rates were 5.6% (knee) and 5.1% (hip) postsurgery versus 1.4% (knee) and 1.3% (hip) presurgery.

CONCLUSION

The overall difference-in-difference results showed a greater decrease in healthcare utilization and costs for the members with joint replacement than for those receiving injection.

摘要

背景

鉴于美国45岁及以上人群中全膝关节和全髋关节置换手术的急剧增加,有必要比较接受关节置换的患者与接受关节内注射作为低成本替代方案的患者的下游医疗保健利用率和成本。

目的

比较接受膝关节或髋关节置换的骨关节炎(OA)医疗保险参保患者与接受类固醇或玻璃酸钠注射的患者在OA相关医疗保健利用率和成本方面的变化。

方法

本回顾性纵向研究纳入了年龄≥45岁且被诊断为OA的医疗保险参保人员。对2007年7月1日至2012年6月30日期间接受初次膝关节或髋关节置换手术的患者以及同期接受止痛药物注射的患者的数据进行比较。关节置换手术日期被视为索引日期。对于比较队列,索引日期为首次关节内注射后180天。从索引前180天到索引后360天,以90天为增量纵向检查医疗和药房索赔。进行差异分析以比较研究队列中索引后与索引前OA相关医疗成本的变化。采用事件发生时间分析来衡量再入院率和静脉血栓栓塞(VTE)发生率。

结果

膝关节置换患者的平均年龄为70.7岁,髋关节置换患者为71.7岁,接受止痛注射的患者为71.1岁(P<.0001)。RxRisk-V合并症指数评分分别为4.7、4.4和4.

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