Zundler Sebastian, Neurath Markus F
a Department of Medicine 1 , University of Erlangen-Nuremberg, Kussmaul Campus for Medical Research & Translational Research Center , Erlangen , Germany.
Expert Rev Clin Immunol. 2016;12(3):233-6. doi: 10.1586/1744666X.2016.1112271. Epub 2015 Nov 11.
Fundamental insights into the pathogenesis of inflammatory bowel diseases (IBD) have led to the development of new therapies and lots of experimental compounds in the pipeline. Our treatment of IBD is therefore constantly evolving. In this editorial, we postulate that bi- or even polyspecific therapy will be an important mainstay of future IBD treatment. Moreover, we highlight some promising new therapeutic concepts currently under investigation and point at the outstanding and growing importance of personalized medicine to assign drugs from the increasing pool of options to the individual patient.
对炎症性肠病(IBD)发病机制的深入了解推动了新疗法的开发以及众多处于研发阶段的实验性化合物的出现。因此,我们对IBD的治疗在不断发展。在这篇社论中,我们推测双特异性甚至多特异性疗法将成为未来IBD治疗的重要支柱。此外,我们强调了目前正在研究的一些有前景的新治疗概念,并指出个性化医疗在从日益增多的药物选择中为个体患者分配药物方面的突出且日益重要的作用。