Thyroid Clinic, General Surgery Service, General Hospital of Mexico , Mexico City, Mexico .
Thyroid. 2016 Jan;26(1):174-8. doi: 10.1089/thy.2015.0190. Epub 2015 Dec 9.
This study investigated whether visual localization of the external branch of the superior laryngeal nerve (EBSLN) coincides with its localization via intraoperative neuro-monitoring (IONM) during thyroidectomy and whether its use influences the frequency of injuries.
A prospective, comparative, cross-sectional, observational study was performed in 240 superior thyroid poles. The metrics were visual identification of the EBSLN and its corroboration with IONM. The frequency of EBSLN injuries was also determined. Statistical analysis was achieved via kappa and chi-square tests, as well as odds ratios (OR).
Of the 240 superior thyroid poles, IONM identified 234 (97.5%) EBSLN, whereas 190 (79.1%) were identified visually: OR = 10.35 [CI 4.37-24.65] p < 0.0001. Of the 190 EBSLN identified visually, 150 were confirmed through IONM. Indeed, their structure corresponded to an EBSLN to yield a kappa with a linear weighting value of 0.362. The standard error was 0.0467 [CI 0.2686-0.4554], indicating a fair agreement between the visual and IONM classification.
IONM identified 97.5% of EBSLN cases. It was higher than the visual identification. There were no injuries to EBSLN identified through IONM.
本研究旨在探讨在甲状腺切除术中,通过术中神经监测(IONM)定位外展神经(EBSLN)是否与视觉定位相吻合,以及其使用是否会影响损伤的频率。
这是一项前瞻性、对比、横断面、观察性研究,共涉及 240 例甲状腺上极。研究指标为 EBSLN 的视觉识别及其与 IONM 的一致性,并确定 EBSLN 损伤的频率。通过 Kappa 和卡方检验以及比值比(OR)进行统计学分析。
在 240 个甲状腺上极中,IONM 识别出 234 个(97.5%)EBSLN,而 190 个(79.1%)通过视觉识别:OR=10.35[95%CI 4.37-24.65]p<0.0001。在通过视觉识别的 190 个 EBSLN 中,有 150 个通过 IONM 得到了确认。实际上,它们的结构与 EBSLN 相对应,Kappa 线性加权值为 0.362。标准误差为 0.0467[95%CI 0.2686-0.4554],表明视觉和 IONM 分类之间存在良好的一致性。
IONM 识别出了 97.5%的 EBSLN 病例,高于视觉识别。通过 IONM 未发现 EBSLN 损伤。