大麦谷物提取物中的抗氧化剂、酶抑制剂和生物活性化合物。

Antioxidants, Enzyme Inhibitors, and Biogenic Compounds in Grain Extracts of Barleys.

作者信息

Maliar Tibor, Slaba Gabriela, Nemeček Peter, Maliarová Mária, Benková Michaela, Havrlentová Michaela, Ondrejovič Miroslav, Kraic Ján

机构信息

Department of Biotechnology, Faculty of Natural Sciences, University of SS. Cyril and Methodius, Nám. J. Herdu 2, SK-91701 Trnava.

Department of Chemistry, Faculty of Natural Sciences, University of SS. Cyril and Methodius, Nám. J. Herdu 2, SK-91701 Trnava.

出版信息

Chem Biodivers. 2015 Nov;12(11):1678-95. doi: 10.1002/cbdv.201400419.

DOI:10.1002/cbdv.201400419

PMID:26567946

Abstract

The content of biogenic compounds and the biological activities of barley (Hordeum vulgare L.)-grain extracts was evaluated. The sufficiently large and heterogeneous set of barley genotypes (100 accessions) enabled the selection of special genotypes interesting for potential industrial, pharmaceutical, and medicinal applications. Barley genotypes with the highest contents of phenols, phenolic acids, flavonoids, biogenic thiols, and amines, radical-scavenging activity, as well as inhibitory activities of trypsin, thrombin, collagenase, urokinase, and cyclooxygenase were identified.

摘要

对大麦（Hordeum vulgare L.）籽粒提取物的生物活性化合物含量及其生物活性进行了评估。数量足够多且具有多样性的大麦基因型（100个品种）使得能够筛选出对潜在工业、制药和医学应用具有重要意义的特殊基因型。鉴定出了酚类、酚酸、黄酮类、生物源硫醇和胺类含量最高、具有自由基清除活性以及对胰蛋白酶、凝血酶、胶原酶、尿激酶和环氧化酶具有抑制活性的大麦基因型。