CAPIS Biomedical Research and Development Department, Mons, Belgium.
Pediatric Cardiovascular, Tehran University of Medical Sciences, Children Medical Center Hospital (Pediatrics Center of Excellence), Tehran, Iran.
J Med Syst. 2016 Jan;40(1):16. doi: 10.1007/s10916-015-0359-3. Epub 2015 Oct 30.
This paper presents a robust device for automated screening of pediatric heart diseases based on our unique processing method in murmur characterization; the Arash-Band method. The present study modifies the Arash-Band method and employs output of the modified method in conjunction with the two other original techniques to extract indicative feature vectors for the screening. The extracted feature vectors are classified by using the support vector machine method. Results show that the proposed modifications significantly enhances performance of the Arash-Band in terms of the both accuracy and sensitivity as the corresponding effect sizes are sufficiently large. The proposed algorithm has been incorporated into an Android-based tablet to constitute an intelligent phonocardiogram with the automatic screening capability. In order to obtain confidence interval of the accuracy and sensitivity, an inferable statistical test is applied on our database containing the phonocardiogram signals recorded from 263 of the referrals to a hospital. The expected value of the accuracy/sensitivity is estimated to be 87.45 % / 87.29 % with a 95 % confidence interval of (80.19 % - 92.47 %) / (76.01 % - 95.78 %) exhibiting superior performance than a pediatric cardiologist who relies on conventional or even computer-assisted auscultation.
本文提出了一种基于我们在杂音特征描述方面的独特处理方法——Arash-Band 方法的小儿心脏病自动筛查的强大设备。本研究对 Arash-Band 方法进行了修改,并将修改后的方法的输出与另外两种原始技术结合起来,以提取用于筛查的指示特征向量。提取的特征向量使用支持向量机方法进行分类。结果表明,所提出的修改在准确性和灵敏度方面显著提高了 Arash-Band 的性能,因为相应的效果大小足够大。该算法已被集成到基于 Android 的平板电脑中,构成具有自动筛查功能的智能心音图。为了获得准确性和灵敏度的置信区间,我们对包含 263 名转诊至医院的患者心音图信号的数据库应用了可推断的统计检验。准确性/灵敏度的预期值估计为 87.45 % / 87.29 %,置信区间为(80.19 % - 92.47 %)/(76.01 % - 95.78 %),表现优于依赖传统听诊甚至计算机辅助听诊的儿科心脏病专家。