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双层自体真皮瓣在复发性和/或感染性切口疝治疗中的应用:手术技术介绍及1年随访结果——一项前瞻性连续队列研究

Use of double-layer autologous dermal flap in the treatment of recurrent and/or infected incisional hernias: presentation of the surgical technique and the results of 1-year follow-up-a prospective, consecutive cohort study.

作者信息

Martis G, Damjanovich L

机构信息

Department of Surgery, University of Debrecen, Health and Science Center, Móricz Zs. krt. 22, Debrecen, 4032, Hungary.

出版信息

Hernia. 2016 Jun;20(3):461-70. doi: 10.1007/s10029-015-1442-x. Epub 2015 Nov 23.

Abstract

INTRODUCTION

The difficulties of treating recurrent and/or infected incisional hernias are well known in surgical practice. Several surgical techniques and various types of grafts are available for surgeons. This study presents a new surgical technique option together with the results of the 1-year follow-up.

PURPOSE

The primary aim of the study is to present the surgical technique of the procedure suitable for the treatment of recurrent and/or infected incisional hernias. The secondary aim is to determine the recurrence rate and analyse the surgical complications. The tertiary aim is to present the quality of life test results performed 3, 6 and 12 months after the surgery.

PATIENTS AND METHOD

The authors evaluated the results of 36 recurrent and/or infected incisional hernia surgeries (11 men, average age 60.6 years; 25 women, average age 58.9 years) performed with their own surgical method in the framework of a tightly controlled, prospective, interventional and observational consecutive cohort study conducted between 1 January 2011 and 31 December 2013 at a university surgical department. The study evaluates the results of the 1-year follow-up period. All 36 patients had at least one recurrence of abdominal wall hernia; 12 of them also had concurrent infection of the synthetic graft and a complicating fistula. The mean BMI was 31.82 kg/m(2) (25.2-43.5 kg/m(2)). The average size of the abdominal wall defect was 145.9 cm(2) (59-275 cm(2)). The abdominal wall reconstruction was performed using an autologous, double-layer dermal flap. The grafts, which had been inserted during previous surgeries, were removed completely. The autologous dermal tissue was prepared using the flap harvested during dermolipectomy. The reconstruction was achieved using a tension-free technique. The essence of the abdominal wall reconstruction is the completion of the abdominal wall defect by a double-layer autologous dermal flap. The original abdominal wall defect was not closed by direct sutures. The quality of the prepared dermal flap was histologically evaluated. IAPMS (intra-abdominal pressure monitoring set) was applied to verify intra-abdominal pressure in the post-operative period. The result of the surgeries was assessed using a quality of life questionnaire.

RESULTS

No recurrence of the abdominal wall hernia was registered during the 1-year follow-up period. Abdominal bulking was observed in case of three patients (8.3 %). Wound infection occurred in one patient (2.77 %) and skin dehiscence in two patients (5.55 %). Haematoma was registered in case of one patient (2.77 %) on the fifth post-operative day. Seroma formation occurred in case of eight patients (22.22 %), which required percutaneous tapping. A fistula formation was observed in one patient (2.77 %) 45 days after the surgery. The intra-abdominal pressure remained moderately elevated during the early post-operative period (9.65-5.76 mmHg on post-operative days 1 and 5). Reoperation was performed in one case due to haematoma. No fatality occurred.

CONCLUSIONS

The 1-year recurrence rate in case of the abdominal wall reconstruction using double-layer autologous dermal flap is favourable. Being compliant with the surgical technique developed, the procedure is safe to perform. The number of surgical site infections and fistula formations is low. Based on the questionnaires evaluated, all patients would choose this method instead of the previous reconstruction(s). The method is cost-effective. Based on the results, this procedure is feasible for the treatment of recurrent and/or infected abdominal wall, incisional ventral hernias in obese "high risk" patients.

摘要

引言

在外科手术实践中,治疗复发性和/或感染性切口疝的困难是众所周知的。外科医生有多种手术技术和各种类型的移植物可供选择。本研究提出了一种新的手术技术选择以及1年随访结果。

目的

本研究的主要目的是介绍适用于治疗复发性和/或感染性切口疝的手术技术。次要目的是确定复发率并分析手术并发症。第三目的是展示术后3个月、6个月和12个月进行的生活质量测试结果。

患者与方法

作者在一所大学外科部门于2011年1月1日至2013年12月31日进行的一项严格控制的前瞻性、干预性和观察性连续队列研究框架内,评估了36例采用其自己手术方法进行的复发性和/或感染性切口疝手术的结果(11名男性,平均年龄60.6岁;25名女性,平均年龄58.9岁)。该研究评估了1年随访期的结果。所有36例患者至少有一次腹壁疝复发;其中12例还同时存在合成移植物感染和并发瘘管。平均体重指数为31.82kg/m²(25.2 - 43.5kg/m²)。腹壁缺损的平均大小为145.9cm²(59 - 275cm²)。使用自体双层皮瓣进行腹壁重建。将先前手术中植入的移植物完全移除。自体真皮组织通过在皮肤切除术中获取的皮瓣制备。采用无张力技术进行重建。腹壁重建的实质是用双层自体皮瓣完成腹壁缺损。原腹壁缺损未通过直接缝合关闭。对制备的皮瓣质量进行组织学评估。在术后使用腹腔内压力监测装置(IAPMS)来验证腹腔内压力。使用生活质量问卷评估手术结果。

结果

在1年随访期内未记录到腹壁疝复发。3例患者(8.3%)出现腹部膨隆。1例患者(2.77%)发生伤口感染,2例患者(5.55%)出现皮肤裂开。1例患者(2.77%)在术后第5天出现血肿。8例患者(22.22%)发生血清肿形成,需要经皮穿刺抽吸。1例患者在术后45天观察到瘘管形成(2.77%)。术后早期腹腔内压力保持中度升高(术后第1天和第5天为9.65 - 5.76mmHg)。1例因血肿进行了再次手术。无死亡病例。

结论

使用双层自体皮瓣进行腹壁重建的1年复发率良好。按照所开发的手术技术操作,该手术是安全的。手术部位感染和瘘管形成的数量较低。根据评估的问卷,所有患者都会选择这种方法而非先前的重建方法。该方法具有成本效益。基于这些结果,该手术对于治疗肥胖“高风险”患者的复发性和/或感染性腹壁切口疝是可行的。

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