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[磷酸生物素和芬诺替丁治疗房室折返性阵发性心动过速的抗心律失常疗效]

[Anti-arrhythmia effectiveness of phosphobion and finoptin in the treatment of atrioventricular retrograde paroxysmal tachycardia].

作者信息

Lukoshiavichiute A I, Gedrimene D A

出版信息

Kardiologiia. 1989 Jan;29(1):21-5.

PMID:2659874
Abstract

Forty-four cases of induced atrioventricular retrograde paroxysmal tachycardia (AVRPT) were studied. AVRPT was provoked by means of frequent esophageal stimulation of the left atrium. During the study, records from the external and esophageal ECG leads were taken. Administration of 10 mg finoptin controlled the AVRPT attack in 86.7% of cases, and the administration of 10 mg fosfobion, in 76.2%. Antegrade block of echo impulse conduction through the atrioventricular node was the electrophysiologic mechanism of AVRPT control in all cases. The time needed to control the attack by the above-mentioned drugs ranged from a few seconds to 5 minutes. Changes of atrioventricular conductivity and patients' subjective sensations were more marked where fosfobion was used.

摘要

对44例诱发性房室逆行性阵发性心动过速(AVRPT)进行了研究。通过频繁食管刺激左心房诱发AVRPT。研究期间,记录体表心电图和食管心电图导联。10mg氟哌啶醇控制了86.7%病例的AVRPT发作,10mg磷霉素控制了76.2%病例的发作。在所有病例中,经房室结的回波冲动传导的前向阻滞是控制AVRPT的电生理机制。上述药物控制发作所需时间从几秒到5分钟不等。使用磷霉素时,房室传导性变化和患者主观感觉更为明显。

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