Ringewald Jeremy M
St Joseph's Children's Hospital, Tampa, Florida, USA.
Curr Opin Cardiol. 2016 Jan;31(1):88-94. doi: 10.1097/HCO.0000000000000241.
Transcatheter pulmonary valve replacement has only been both approved and widely available for most congenital heart disease centers for a few years; its use and familiarity for interventionalists have greatly expanded our knowledge of its applicability to a multitude of clinical situations. Expanded worldwide use and longer time from implant have both served to better understand procedural limits and uncommon late adverse events.
Although currently approved for implantation in the USA only in dysfunctional and circumferential right ventricle to pulmonary artery conduits, with expanded experience operators have been able to adapt the delivery of this valve in a large number of additional clinical scenarios. Rare technical limitations of the procedure, most importantly coronary compression, are now being better defined. Although not frequent, a significant number of infective endocarditis episodes have been reported, but more recently several studies have deepened our understanding of this late adverse event for the most commonly implanted transcatheter pulmonary valve prosthesis.
Expanded and widened use has extended our understanding of who may benefit from transcatheter pulmonary valve implantation (TPVI), the current limits of TPVI, and uncommon but important late issues following TPVI.
经导管肺动脉瓣置换术在多数先天性心脏病中心获得批准并广泛应用仅数年时间;介入医生对其的使用和熟悉程度极大地拓展了我们对其在多种临床情况中适用性的认识。在全球范围内的广泛应用以及植入后更长的时间,都有助于更好地了解该手术的局限性和罕见的晚期不良事件。
尽管目前在美国仅批准将其植入功能失调的右心室至肺动脉管道以及环形管道,但随着经验的积累,操作人员已能够在大量其他临床场景中应用该瓣膜。该手术罕见的技术局限性,最重要的是冠状动脉受压,目前正得到更好的界定。尽管感染性心内膜炎发作并不常见,但已有大量相关报道,不过最近的几项研究加深了我们对最常用的经导管肺动脉瓣假体这一晚期不良事件的理解。
应用范围的扩大和拓展加深了我们对哪些人可能从经导管肺动脉瓣植入术(TPVI)中获益、TPVI当前的局限性以及TPVI后罕见但重要的晚期问题的认识。