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[一名心房颤动和心力衰竭患者的复发性右心房血栓]

[Recurrent right atrial thrombus in a patient with atrial fibrillation and heart failure].

作者信息

Elikowski Waldemar, Wróblewski Dariusz, Małek-Elikowska Małgorzata, Mazurek Andrzej, Foremska-Iciek Joanna, Łazowski Stanisław

机构信息

Józef Struś Hospital, Poznań, Poland: Department of Internal Medicine.

University of Medical Sciences, 2nd Department of Cardiology, Poznań, Poland.

出版信息

Pol Merkur Lekarski. 2015 Nov;39(233):316-20.

Abstract

Atrial fibrillation and heart failure are factors predisposing to locally formed intracardiac thrombosis, which is usually localized in left-sided chambers. A case report. The authors present a case of a 50-year-old male with permanent atrial fibrillation and dilated cardiomyopathy in whom recurrent right atrial thrombus was observed. Initially, the lesion was detected in echocardiography while he was hospitalized due to extensive right-sided pneumonia. The thrombus was successfully treated with heparin, followed by warfarin. Even though the patient continued warfarin use properly, there was recurrence of the thrombus two years later during a new episode of heart failure exacerbation. Because the thrombus was resistant to intensified anticoagulation, cardiac surgery was needed. A large (30 x 25 mm) pedunculated thrombus, as well as two smaller ones (each of 10 x 10 mm) attached closely to the atrial wall and previously not detected either by echocardiography or by magnetic resonance imaging, were excited. A partially organized pattern of the thrombi in histological examination can explain lack of anticoagulation effectiveness.

摘要

心房颤动和心力衰竭是易导致心腔内局部形成血栓的因素,这种血栓通常位于左侧心腔。病例报告。作者介绍了一例50岁男性患者,患有永久性心房颤动和扩张型心肌病,观察到其右心房反复出现血栓。最初,在他因广泛右侧肺炎住院期间,经超声心动图检测到该病变。血栓先用肝素成功治疗,随后使用华法林。尽管患者持续正确使用华法林,但两年后在心力衰竭加重的新发作期间血栓复发。由于血栓对抗凝强化治疗有抵抗,需要进行心脏手术。切除了一个大的(30×25毫米)有蒂血栓,以及两个紧密附着于心房壁且之前经超声心动图或磁共振成像均未检测到的较小血栓(每个10×10毫米)。组织学检查中血栓的部分机化模式可以解释抗凝治疗无效的原因。

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