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院外心脏骤停(OHCA)后影响生存的空间变异与复苏过程

Spatial Variation and Resuscitation Process Affecting Survival after Out-of-Hospital Cardiac Arrests (OHCA).

作者信息

Chen Chien-Chou, Chen Chao-Wen, Ho Chi-Kung, Liu I-Chuan, Lin Bo-Cheng, Chan Ta-Chien

机构信息

Center for Geographic Information Science, Research Center for Humanities and Social Sciences, Academia Sinica, Taipei, Taiwan.

Division of Trauma, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

出版信息

PLoS One. 2015 Dec 14;10(12):e0144882. doi: 10.1371/journal.pone.0144882. eCollection 2015.

Abstract

BACKGROUND

Ambulance response times and resuscitation efforts are critical predictors of the survival rate after out-of-hospital cardiac arrests (OHCA). On the other hand, rural-urban differences in the OHCA survival rates are an important public health issue.

METHODS

We retrospectively reviewed the January 2011-December 2013 OHCA registry data of Kaohsiung City, Taiwan. With particular focus on geospatial variables, we aimed to unveil risk factors predicting the overall OHCA survival until hospital admission. Spatial analysis, network analysis, and the Kriging method by using geographic information systems were applied to analyze spatial variations and calculate the transport distance. Logistic regression was used to identify the risk factors for OHCA survival.

RESULTS

Among the 4,957 patients, the overall OHCA survival to hospital admission was 16.5%. In the multivariate analysis, female sex (adjusted odds ratio:, AOR, 1.24 [1.06-1.45]), events in public areas (AOR: 1.30 [1.05-1.61]), exposure to automated external defibrillator (AED) shock (AOR: 1.70 [1.30-2.23]), use of laryngeal mask airway (LMA) (AOR: 1.35 [1.16-1.58]), non-trauma patients (AOR: 1.41 [1.04-1.90]), ambulance bypassed the closest hospital (AOR: 1.28 [1.07-1.53]), and OHCA within the high population density areas (AOR: 1.89 [1.55-2.32]) were positively associated with improved OHCA survival. By contrast, a prolonged total emergency medical services (EMS) time interval was negatively associated with OHCA survival (AOR: 0.98 [0.96-0.99]).

CONCLUSIONS

Resuscitative efforts, such as AED or LMA use, and a short total EMS time interval improved OHCA outcomes in emergency departments. The spatial heterogeneity of emergency medical resources between rural and urban areas might affect survival rate.

摘要

背景

救护车响应时间和复苏努力是院外心脏骤停(OHCA)后存活率的关键预测因素。另一方面,OHCA存活率的城乡差异是一个重要的公共卫生问题。

方法

我们回顾性分析了台湾高雄市2011年1月至2013年12月的OHCA登记数据。特别关注地理空间变量,旨在揭示预测OHCA患者入院前总体存活率的危险因素。运用地理信息系统进行空间分析、网络分析和克里金法,以分析空间变异并计算转运距离。采用逻辑回归确定OHCA存活的危险因素。

结果

在4957例患者中,OHCA患者入院前的总体存活率为16.5%。多因素分析显示,女性(调整优势比[AOR]:1.24[1.06 - 1.45])、公共场所发生的事件(AOR:1.30[1.05 - 1.61])、接受自动体外除颤器(AED)电击(AOR:1.70[1.30 - 2.23])、使用喉罩气道(LMA)(AOR:1.35[1.16 - 1.58])、非创伤患者(AOR:1.41[1.04 - 1.90])、救护车绕过最近的医院(AOR:1.28[1.07 - 1.53])以及高人口密度地区的OHCA(AOR:1.89[1.55 - 2.32])与OHCA存活率提高呈正相关。相比之下,总紧急医疗服务(EMS)时间间隔延长与OHCA存活率呈负相关(AOR:0.98[0.96 - 0.99])。

结论

诸如使用AED或LMA等复苏努力以及较短的总EMS时间间隔可改善急诊科OHCA的治疗结果。城乡地区紧急医疗资源的空间异质性可能影响存活率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/483f/4682793/c6a5005355cd/pone.0144882.g001.jpg

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