Bugshan Amr, Patel Harsh, Garber Karen, Meiller Timothy F
Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, Md., USA.
Case Rep Oncol. 2015 Nov 14;8(3):493-7. doi: 10.1159/000441839. eCollection 2015 Sep-Dec.
Pyogenic granulomas (PGs) in the oral cavity present as an inflammatory hyperplasia usually caused by trauma, hormonal imbalance, chronic irritation, or as the response to a wide variety of drugs. PGs with atypical presentation and behavior may clinically mimic malignant tumors. Thus, histological examination is required to rule out cancer development. Lesions in the oral cavity have been described to be either an isolated entity or present in multiple forms and with multiple recurrences. Conservative surgical excision is the standard choice of treatment in almost every scenario. However, the severity of the lesions and the affected sites often challenge surgical treatment. In this report, we describe the clinical scenario of a recurrent PG, where surgical excision of the lesion was questioned. As an alternative, we describe a noninvasive approach with lesional steroid injections.
口腔化脓性肉芽肿（PGs）表现为一种炎症性增生，通常由创伤、激素失衡、慢性刺激引起，或作为对多种药物的反应。具有非典型表现和行为的PGs在临床上可能类似于恶性肿瘤。因此，需要进行组织学检查以排除癌症发展。口腔病变已被描述为孤立的实体，或呈多种形式并多次复发。在几乎每种情况下，保守性手术切除都是标准的治疗选择。然而，病变的严重程度和受累部位常常对手术治疗构成挑战。在本报告中，我们描述了一例复发性PG的临床情况，其中对病变的手术切除提出了质疑。作为一种替代方法，我们描述了一种病灶内注射类固醇的非侵入性方法。
