Trencsényi György, Barna Sándor Kristóf, Garai Ildikó
ScanoMed Orvosi, Diagnosztikai, Kutató és Oktató Kft. Debrecen, Nagyerdei krt. 98., 4032.
Orv Hetil. 2015 Dec 27;156(52):2110-5. doi: 10.1556/650.2015.30324.
Nowadays the hybrid imaging technologies which combine the modern equipments of radiology and nuclear medicine play an important role in both the translational research process and clinical diagnostics. Among the routine diagnostic imaging procedures positron emission tomography and single photon emission computed tomography combined with computed tomography or magnetic resonance imaging currently belong to the most advanced techniques allowing that functional and morphological images can be superimposed on each other in the same position. The hybrid imaging equipments provide useful information about the pathological processes in the body due to their high sensibility and resolution. Furthermore, with the help of these imaging modalities we can get acquainted with the biochemical and pathobiochemical processes that are essential for understanding and treating diseases, or getting acquainted with the behaviour of a new drug candidate. With the help of the clinical and preclinical non-invasive in vivo molecular imaging systems the drug developing process can be shortened and its costs can be reduced.
如今,结合了放射学和核医学现代设备的混合成像技术在转化研究过程和临床诊断中都发挥着重要作用。在常规诊断成像程序中,正电子发射断层扫描和单光子发射计算机断层扫描与计算机断层扫描或磁共振成像相结合,目前属于最先进的技术,能够使功能图像和形态图像在同一位置相互叠加。混合成像设备因其高灵敏度和分辨率,可提供有关体内病理过程的有用信息。此外,借助这些成像方式,我们可以了解对疾病的理解和治疗至关重要的生化和病理生化过程,或者了解新候选药物的行为。借助临床和临床前非侵入性体内分子成像系统,可以缩短药物研发过程并降低成本。