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英国颅部立体定向放射外科的现状

Current status of cranial stereotactic radiosurgery in the UK.

作者信息

Dimitriadis Alexis, Kirkby Karen J, Nisbet Andrew, Clark Catharine H

机构信息

1 Department of Physics, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, UK.

2 Department of Medical Physics, Royal County Hospital NHS Foundation Trust, Guildford, UK.

出版信息

Br J Radiol. 2016;89(1058):20150452. doi: 10.1259/bjr.20150452. Epub 2015 Dec 21.

Abstract

OBJECTIVE

To investigate and benchmark the current clinical and dosimetric practices in stereotactic radiosurgery (SRS) in the UK.

METHODS

A detailed questionnaire was sent to 70 radiotherapy centres in the UK. 97% (68/70) of centres replied between June and December 2014.

RESULTS

21 centres stated that they are practising SRS, and a further 12 centres plan to start SRS by the end of 2016. The most commonly treated indications are brain metastases and acoustic neuromas. A large range of prescription isodoses that range from 45% to 100% between different radiotherapy centres was seen. Ionization chambers and solid-water phantoms are used by the majority of centres for patient-specific quality assurance, and thermoplastic masks for patient immobilization are more commonly used than fixed stereotactic frames. The majority of centres perform orthogonal kilovoltage X-rays for localization before and during delivery. The acceptable setup accuracy reported ranges from 0.1 to 2 mm with a mean of 0.8 mm.

CONCLUSION

SRS has been increasing in use in the UK and will continue to increase in the next 2 years. There is no current consensus between SRS centres as a whole, or even between SRS centres with the same equipment, on the practices followed. This indicates the need for benchmarking and standardization in SRS practices within the UK.

ADVANCES IN KNOWLEDGE

This article outlines the current practices in SRS and provides a benchmark for reference and comparison with future research in this technique.

摘要

目的

调查并评估英国立体定向放射外科(SRS)当前的临床和剂量测定实践。

方法

向英国70家放疗中心发送了一份详细问卷。2014年6月至12月期间,97%(68/70)的中心进行了回复。

结果

21家中心表示他们正在开展SRS,另有12家中心计划在2016年底前开始开展SRS。最常见的治疗适应症是脑转移瘤和听神经瘤。不同放疗中心之间的处方等剂量范围差异很大,从45%到100%不等。大多数中心使用电离室和固体水模体进行患者特异性质量保证,与固定立体定向框架相比,热塑性面罩更常用于患者固定。大多数中心在放疗前和放疗过程中进行正交千伏X射线定位。报告的可接受设置精度范围为0.1至2毫米,平均为0.8毫米。

结论

SRS在英国的使用一直在增加,未来两年还将继续增加。目前,整个SRS中心之间,甚至使用相同设备的SRS中心之间,在遵循的实践方面都没有达成共识。这表明英国SRS实践需要进行基准测试和标准化。

知识进展

本文概述了SRS的当前实践,并为该技术的未来研究提供了一个可供参考和比较的基准。

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