Chung L P, Lake F, Hyde E, McCamley C, Phuangmalai N, Lim M, Waterer G, Summers Q, Moodley Y
Department of Respiratory and Sleep Medicine, Royal Perth Hospital, Perth, Western Australia, Australia.
Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Intern Med J. 2016 Apr;46(4):427-34. doi: 10.1111/imj.12984.
Hospitalisations for chronic obstructive pulmonary disease (COPD) exacerbation affect patient outcomes and healthcare costs. The long-term impact of an integrated COPD disease-management approach on hospitalisation remains controversial.
The aim of this study was to evaluate whether a multidisciplinary community service reduces respiratory hospitalisations for COPD patients.
A total of 346 patients was followed for a mean duration of 27.3 months. The number of admissions, total bed days for respiratory (COPD exacerbation or pneumonia) or general medical causes and length of stay (LOS) per respiratory admission was compared before and after referral with the service. A secondary multivariate analysis examined which clinical parameters best predict benefit from such service.
The total respiratory admission and hospital bed days after referral were reduced by 31% (288 vs 417, P < 0.001) and 40.4% (1637 vs 2746, P < 0.0001) respectively, compared with the equivalent duration prior. The average LOS for each respiratory admission was also significantly reduced after referral (6.61 vs 5.70, P = 0.02). Overall, 55% patients experienced a reduction in admission frequency and hospital days. The impact on admission frequency and hospital days was the greatest in those with an at least moderate disease (GOLD ≥2, odds ratio (OR): 3.2, 95% confidence interval (CI): 1.2, 8.9; P = 0.019) and those who completed pulmonary rehabilitation (PR) (OR: 1.7, 95% CI: 1.1, 2.8; P = 0.04). In contrast, general medical admissions increased, one-third attributable to a cardiovascular cause both before and after referral.
The implementation of COPD multidisciplinary community service was associated with reduced respiratory hospitalisations in the long term. Patients with moderate or severe disease and who are able to complete PR are much more likely to benefit.
慢性阻塞性肺疾病(COPD)急性加重导致的住院会影响患者预后及医疗费用。COPD综合疾病管理方法对住院的长期影响仍存在争议。
本研究旨在评估多学科社区服务是否能减少COPD患者的呼吸道住院次数。
共对346例患者进行了平均27.3个月的随访。比较了转诊至该服务前后的住院次数、因呼吸道疾病(COPD急性加重或肺炎)或一般医疗原因的总住院天数以及每次呼吸道住院的住院时长(LOS)。二次多变量分析研究了哪些临床参数最能预测从该服务中获益。
与之前相同时间段相比,转诊后的呼吸道总住院次数和住院天数分别减少了31%(288次对417次,P<0.001)和40.4%(1637天对2746天,P<0.0001)。每次呼吸道住院的平均LOS在转诊后也显著缩短(6.61天对5.70天,P=0.02)。总体而言,55%的患者住院频率和住院天数减少。对住院频率和住院天数的影响在至少患有中度疾病(慢性阻塞性肺疾病全球倡议(GOLD)分级≥2级,优势比(OR):3.2,95%置信区间(CI):1.2,8.9;P=0.019)的患者以及完成肺康复(PR)的患者中最为显著(OR:1.7,95%CI:1.1,2.8;P=0.04)。相比之下,一般医疗住院次数增加,其中三分之一在转诊前后均归因于心血管原因。
COPD多学科社区服务的实施与长期呼吸道住院次数减少相关。患有中度或重度疾病且能够完成PR的患者更有可能从中获益。