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The indirect pathway of the nucleus accumbens shell amplifies neuropathic pain.
Nat Neurosci. 2016 Feb;19(2):220-2. doi: 10.1038/nn.4199. Epub 2015 Dec 21.
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Persistent neuropathic pain increases synaptic GluA1 subunit levels in core and shell subregions of the nucleus accumbens.
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Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain.
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Galanin plays a role in antinociception via binding to galanin receptors in the nucleus accumbens of rats with neuropathic pain.
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Tumor suppressor menin mediates peripheral nerve injury-induced neuropathic pain through potentiating synaptic plasticity.
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Role of nucleus accumbens in neuropathic pain: linked multi-scale evidence in the rat transitioning to neuropathic pain.
Pain. 2014 Jun;155(6):1128-1139. doi: 10.1016/j.pain.2014.02.019. Epub 2014 Mar 6.

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Chronic pain selectively reduces the motivation to work for remifentanil but not food reward.
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The causal role of brain circuits in osteoarthritis pain.
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Estradiol protects against pain-facilitated fentanyl use via suppression of opioid-evoked dopamine activity in males.
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本文引用的文献

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Activation of corticostriatal circuitry relieves chronic neuropathic pain.
J Neurosci. 2015 Apr 1;35(13):5247-59. doi: 10.1523/JNEUROSCI.3494-14.2015.
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Chemogenetic tools to interrogate brain functions.
Annu Rev Neurosci. 2014;37:387-407. doi: 10.1146/annurev-neuro-071013-014048. Epub 2014 Jun 16.
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Role of nucleus accumbens in neuropathic pain: linked multi-scale evidence in the rat transitioning to neuropathic pain.
Pain. 2014 Jun;155(6):1128-1139. doi: 10.1016/j.pain.2014.02.019. Epub 2014 Mar 6.
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Parceling human accumbens into putative core and shell dissociates encoding of values for reward and pain.
J Neurosci. 2013 Oct 9;33(41):16383-93. doi: 10.1523/JNEUROSCI.1731-13.2013.
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Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens.
Neuron. 2012 Nov 21;76(4):790-803. doi: 10.1016/j.neuron.2012.09.040.
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Diversity in NMDA receptor composition: many regulators, many consequences.
Neuroscientist. 2013 Feb;19(1):62-75. doi: 10.1177/1073858411435129. Epub 2012 Feb 17.
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Modulation of striatal projection systems by dopamine.
Annu Rev Neurosci. 2011;34:441-66. doi: 10.1146/annurev-neuro-061010-113641.
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Chronic dizocilpine or apomorphine and development of neuropathy in two rat models I: behavioral effects and role of nucleus accumbens.
Exp Neurol. 2011 Mar;228(1):19-29. doi: 10.1016/j.expneurol.2010.12.004. Epub 2010 Dec 10.

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