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向非美国公民及非美国居民分配肝脏:一种排后优先法的伦理框架。

Liver Allocation to Non-U.S. Citizen Non-U.S. Residents: An Ethical Framework for a Last-in-Line Approach.

作者信息

Hartsock J A, Ivy S S, Helft P R

机构信息

Indiana University School of Liberal Arts, Indianapolis, IN.

Indiana University Health, Indianapolis, IN.

出版信息

Am J Transplant. 2016 Jun;16(6):1681-7. doi: 10.1111/ajt.13674. Epub 2016 Feb 3.

Abstract

The incidence of non-U.S. citizen non-U.S. resident patients coming to the United States specifically for deceased donor liver transplantation raises compelling ethical questions that require careful consideration. The inclusion of these often financially and/or socially privileged patients in the pool of potential candidates for an absolutely scarce and life-saving liver transplant may exacerbate disparities already existing in deceased donor liver allocation. In addition, their inclusion on organ transplant waiting lists conflicts with recognized ethical principles of justice and reciprocity. Moreover, preliminary data suggest that public awareness of this practice could discourage organ donation, thereby worsening an already profound supply-demand gulf. Finally, U.S. organ allocation policies and statutes are out of step with recently promulgated international transplant guidelines, which prioritize self-sufficiency of organ programs. This article analyzes each of these ethical conflicts within the context of deceased donor liver transplantation and recommends policy changes that align the United States with international practices that discourage this scenario.

摘要

非美国公民且非美国居民专门前往美国进行已故捐赠者肝脏移植的情况日益增多,这引发了一系列引人深思的伦理问题,需要我们审慎对待。将这些通常在经济和/或社会上享有特权的患者纳入绝对稀缺且能救命的肝脏移植潜在候选者群体,可能会加剧已故捐赠者肝脏分配中业已存在的不平等现象。此外,将他们列入器官移植等待名单,与公认的公正和互惠伦理原则相冲突。再者,初步数据表明,公众对这种做法的认知可能会抑制器官捐赠,从而使原本就极为严重的供需差距进一步恶化。最后,美国的器官分配政策和法规与最近颁布的国际移植指南不一致,后者强调器官项目的自给自足。本文在已故捐赠者肝脏移植的背景下分析了这些伦理冲突,并建议进行政策调整,使美国与国际上不鼓励这种情况的做法保持一致。

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