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参与一项心理治疗研究的双相情感障碍青少年的自杀未遂和非自杀性自伤的预期发生率。

Prospective rates of suicide attempts and nonsuicidal self-injury by young people with bipolar disorder participating in a psychotherapy study.

作者信息

Inder Maree L, Crowe Marie T, Luty Suzanne E, Carter Janet D, Moor Stephanie, Frampton Christopher M, Joyce Peter R

机构信息

Department of Psychological Medicine, University of Otago - Christchurch, Christchurch, New Zealand

Department of Psychological Medicine, University of Otago - Christchurch, Christchurch, New Zealand.

出版信息

Aust N Z J Psychiatry. 2016 Feb;50(2):167-73. doi: 10.1177/0004867415622268. Epub 2015 Dec 23.

Abstract

OBJECTIVE

Bipolar disorder is a chronic relapsing disorder associated with high rates of suicide, suicide attempts and nonsuicidal self-injury. The study aimed to prospectively identify the rates of suicide attempts and nonsuicidal self-injury in young people participating in an adjunctive randomised controlled psychotherapy for bipolar disorder and to identify differences in individuals who engaged in nonsuicidal self-injury, made suicide attempts or did both.

METHOD

In all, 100 participants aged 15-36 years with bipolar disorder received 78 weeks of psychotherapy and were followed up for a further 78 weeks. Data were collected using the Longitudinal Interval Follow-up Evaluation.

RESULTS

Suicide attempts reduced from 11% at baseline to 1% at the end of follow-up (week 156). Similarly, self-harm reduced from 15% at baseline to 7% at the end of follow-up. Individuals who engaged in both nonsuicidal self-injury and made suicide attempts differed from those with who only made suicide attempts, engaged in nonsuicidal self-injury or did neither. They were characterised by a younger age of illness onset and higher comorbidity.

CONCLUSION

Adjunctive intensive psychotherapy may be effective in reducing suicide attempts and nonsuicidal self-injury and warrants further attention. Particular attention needs to be paid to individuals with early age of onset of bipolar disorder.

摘要

目的

双相情感障碍是一种慢性复发性疾病,与高自杀率、自杀未遂率和非自杀性自伤率相关。本研究旨在前瞻性地确定参与双相情感障碍辅助随机对照心理治疗的年轻人的自杀未遂率和非自杀性自伤率,并确定那些进行非自杀性自伤、自杀未遂或两者皆有的人之间的差异。

方法

共有100名年龄在15 - 36岁的双相情感障碍患者接受了78周的心理治疗,并进一步随访78周。使用纵向间隔随访评估收集数据。

结果

自杀未遂率从基线时的11%降至随访结束时(第156周)的1%。同样,自伤率从基线时的15%降至随访结束时的7%。那些既进行非自杀性自伤又有自杀未遂行为的人与那些仅自杀未遂、仅进行非自杀性自伤或两者皆无的人有所不同。他们的特点是发病年龄较轻且合并症较多。

结论

辅助强化心理治疗可能对降低自杀未遂率和非自杀性自伤率有效,值得进一步关注。需要特别关注双相情感障碍发病年龄较早的个体。

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