Hesh Christopher A, Young Ezekiel, Intihar Paul, Gearhart John P
The Johns Hopkins School of Medicine, Department of Urology, Division of Pediatric Urology, Baltimore, MD, United States.
The Johns Hopkins School of Medicine, Department of Urology, Division of Pediatric Urology, Baltimore, MD, United States.
J Pediatr Surg. 2016 Aug;51(8):1312-6. doi: 10.1016/j.jpedsurg.2015.11.011. Epub 2015 Nov 24.
Failure of primary closure in classic bladder exstrophy (CBE) is a significant cause of morbidity, and yet its relative economic impact has not been well characterized. The authors aim to determine whether CBE patients who underwent failed primary closure incur greater economic burden in the year following their successful closure than those patients who underwent a successful primary closure.
After institutional review board approval CBE patients who were successfully closed between 1993 and 2013 were identified in an institutional exstrophy-epispadias database. Patients who were never closed at the study institution and those who had no documented successful closure were excluded. Inpatient hospital charges, hospital costs, and professional fees were collected for the year following successful closure.
162 patients met the inclusion and exclusion criteria and accounted for 312 inpatient admissions in the year following and including their respective successful bladder closures. 62 of the patients failed their primary closure and the remaining 100 succeeded. Adjusting for covariates, patients who underwent successful primary closure experienced a reduction in inpatient hospital charges of $8497, hospital costs of $9046 and professional fees of $11,180 in the year following their successful closure compared to those patients who failed their primary closure.
Apart from the self-evident financial advantages of a successful primary closure, namely the avoidance of reclosure, there appears to be a lasting negative financial impact of failed primary closure even after these patients undergo successful reclosure at the study institution.
经典膀胱外翻(CBE)一期缝合失败是发病的一个重要原因,但其相对经济影响尚未得到充分描述。作者旨在确定一期缝合失败的CBE患者在成功缝合后的一年中是否比一期缝合成功的患者承担更大的经济负担。
经机构审查委员会批准,在机构性膀胱外翻-尿道上裂数据库中识别出1993年至2013年间成功缝合的CBE患者。排除在研究机构从未进行缝合以及没有记录成功缝合的患者。收集成功缝合后一年的住院费用、医院成本和专业费用。
162例患者符合纳入和排除标准,在包括各自成功膀胱缝合后的一年中共计312次住院。其中62例患者一期缝合失败,其余100例成功。在调整协变量后,与一期缝合失败的患者相比,一期缝合成功的患者在成功缝合后的一年中,住院费用减少了8497美元,医院成本减少了9046美元,专业费用减少了11180美元。
除了一期缝合成功所带来的显而易见的经济优势,即避免再次缝合外,即使这些患者在研究机构成功进行再次缝合后,一期缝合失败似乎仍会产生持久的负面经济影响。