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双相障碍患者自杀未遂史与家庭功能的关系。

Association between history of suicide attempts and family functioning in bipolar disorder.

机构信息

Bipolar Disorder Program (PROMAN), Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.

Bipolar Disorder Program (PROMAN), Department of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.

出版信息

J Affect Disord. 2016 Mar 1;192:28-33. doi: 10.1016/j.jad.2015.12.010. Epub 2015 Dec 12.

Abstract

OBJECTIVES

To investigate the association between history of suicide attempts (SA) and family functioning in bipolar disorder (BD) patients.

METHODS

Thirty-one BD type I patients with lifetime history of SA, 31 BD type I with no lifetime history of SA, participating in the Outpatient Clinic of the Bipolar Disorder Program at the Institute of Psychiatry of the University of São Paulo Medical School were recruited for this study. We used the Family Assessment Device (FAD) to evaluate family functioning. We compared these two groups on demographic and clinical variables to identify which variables were associated with family functioning impairment. Fifty-one relatives of the same patients were also asked to complete a FAD.

RESULTS

BD patients with SA presented more psychiatric hospitalizations, higher frequency of psychotic symptoms, and higher scores on depressive, manic, and suicidal ideation than BD patients without SA. BD patients with SA presented significantly higher scores in several subscales of the FAD, including Problem Solving (p=0.042), Communication (p=0.009), Roles (p=0.006), and General Functioning (p=0.025), when compared with BD patients without SA. Relatives of BD patients with SA presented significantly higher scores in Communication, Roles, Affective Responsiveness, and General Functioning than relatives of BD patients without SA.

LIMITATIONS

Cross-sectional study and long time elapsed since last SA.

CONCLUSION

History of SA in BD is associated with worse family functioning in several domains of FAD, including Problem Solving, Communication, Roles, and General Functioning. As suicide attempts are routinely assessed in clinical practice, these findings may help to identify patients with poorer family functioning and may suggest a role for environmental risk factors in suicidal behavior among BD patients.

摘要

目的

探讨双相障碍(BD)患者自杀未遂(SA)史与家庭功能的关系。

方法

本研究纳入了 31 例有 SA 史的 BD I 型患者和 31 例无 SA 史的 BD I 型患者,他们均来自于圣保罗大学医学院精神病学系门诊诊所的双相障碍项目。我们使用家庭评估工具(FAD)来评估家庭功能。我们比较了这两组患者的人口统计学和临床变量,以确定哪些变量与家庭功能障碍有关。同时,还要求 51 名患者亲属填写 FAD。

结果

与无 SA 史的 BD 患者相比,有 SA 史的 BD 患者有更多的精神科住院经历、更高的精神病性症状频率、更严重的抑郁、躁狂和自杀意念。有 SA 史的 BD 患者在 FAD 的几个子量表中得分显著更高,包括解决问题(p=0.042)、沟通(p=0.009)、角色(p=0.006)和一般功能(p=0.025)。与无 SA 史的 BD 患者相比,有 SA 史的 BD 患者亲属在沟通、角色、情感反应和一般功能方面的得分也显著更高。

局限性

这是一项横断面研究,且距离最近一次 SA 发生的时间较长。

结论

BD 患者有 SA 史与 FAD 的多个领域的家庭功能较差有关,包括解决问题、沟通、角色和一般功能。由于在临床实践中经常评估自杀未遂,这些发现可能有助于识别家庭功能较差的患者,并可能提示环境风险因素在 BD 患者自杀行为中的作用。

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