非霍奇金淋巴瘤患者双侧手部鳞状细胞癌。病例报告及文献综述。
Bilateral hand squamous-cells carcinoma in patient affected with non-Hodgkin lymphoma. Case report and literature review.
作者信息
Fino P, Spagnoli A M, Ruggieri M, Marcasciano M, Scuderi N
出版信息
G Chir. 2015 Jul-Aug;36(4):172-82. doi: 10.11138/gchir/2015.36.4.172.
BACKGROUND
Squamous-cell skin cancer is the most frequent tumor in the hand. It occurs on sun-damaged skin, especially in lightskinned individuals with a long history of chronic sun exposure.
CASE REPORT
We describe a case of bilateral hand squamous-cell carcinoma in a elderly patient affected with non-Hodgkin's lymphoma, who underwent several non-successful surgical treatment, radiotherapy and at the least, amputation of right hand for rapid clinical evolution after radiotreatment. Available literature on the subject has been reviewed.
RESULTS
In our case, after several non-successful treatment, elective amputation at the distal third of forearm was performed. We reviewed 56 items including books, original articles, reviews, cases report.
CONCLUSIONS
Current evidence on treatment of hand squamouscells carcinoma is to perform a first radical surgical treatment in order to avoid recurrence/metastasis and to achieve a safer level of amputation thus increasing the surface area of healthy tissue available for eventually subsequent reconstruction/prosthesization.
背景
鳞状细胞皮肤癌是手部最常见的肿瘤。它发生在受阳光损伤的皮肤上，尤其多见于长期慢性日晒的浅肤色个体。
病例报告
我们描述了一例老年非霍奇金淋巴瘤患者双侧手部鳞状细胞癌的病例，该患者接受了多次手术治疗均未成功，还接受了放疗，最后因放疗后病情迅速发展而进行了右手截肢。我们对该主题的现有文献进行了综述。
结果
在我们的病例中，经过多次治疗失败后，在前臂远端三分之一处进行了选择性截肢。我们查阅了56篇文献，包括书籍、原创文章、综述、病例报告。
结论
目前关于手部鳞状细胞癌治疗的证据表明，应首先进行根治性手术治疗，以避免复发/转移，并实现更安全的截肢水平，从而增加最终用于后续重建/假体植入的健康组织表面积。
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