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前路减压融合钢板固定治疗神经根型或脊髓型颈椎病后的深部手术部位感染

Deep surgical site infection after anterior decompression and fusion with plate fixation for cervical spondylotic radiculopathy or myelopathy.

作者信息

Guo Qunfeng, Zhang Mei, Wang Liang, Lu Xuhua, Ni Bin

机构信息

Department of Orthopedics, Changzheng Hospital, The Second Military Medical University, Shanghai, People's Republic of China.

Department of Traditional Chinese Medicine Rehabilitation, Zhabei Central Hospital, Shanghai, People's Republic of China.

出版信息

Clin Neurol Neurosurg. 2016 Feb;141:13-8. doi: 10.1016/j.clineuro.2015.11.003. Epub 2015 Nov 10.

Abstract

OBJECTIVES

To analyze the diagnosis and management of deep surgical site infection (SSI) with implant involved after anterior decompression and fusion for cervical spondylotic radiculopathy/myelopathy (CSR/CSM).

PATIENTS AND METHODS

Data of the patients who underwent anterior cervical decompression and fusion with plate fixation due to CSR/CSM were retrospectively reviewed. Cases with postoperative deep SSI with implant involved were identified and analyzed.

RESULTS

A total of 1287 patients were finally included. Five patients (0.4%) were found to be with deep SSI. Bone fusion was not obtained when SSI was confirmed in each patient. Three cases were cured using one or two debridement and postoperative antibiotic therapy. Two cases with delayed diagnosis needed anterior implants removal, interbody fusion with autologous iliac bone and posterior lateral mass screw fixation at the first/second debridement. One of the two patients developed esophagus perforation after a second debridement and experienced one-month open drainage. All of the patients were cured without relapse of infection.

CONCLUSION

For early deep SSI after anterior cervical decompression and fusion, surgical debridement was effective to eradicate infection. But for cases with delayed diagnosis, anterior debridement with prophylactic implant removal and posterior reconstruction was an ideal option. Esophagus perforation complicated with multiple debridements should be paid attention to and avoided.

摘要

目的

分析神经根型/脊髓型颈椎病(CSR/CSM)前路减压融合术后深部手术部位感染(SSI)合并植入物的诊断与处理。

患者与方法

回顾性分析因CSR/CSM接受前路颈椎减压融合钢板内固定术患者的数据。确定并分析术后深部SSI合并植入物的病例。

结果

最终纳入1287例患者。5例(0.4%)发生深部SSI。确诊SSI时,每例患者均未实现骨融合。3例经1次或2次清创及术后抗生素治疗后治愈。2例诊断延误的患者在首次/第二次清创时需要取出前路植入物,行自体髂骨椎间融合及后路侧块螺钉固定。2例患者中有1例在第二次清创后发生食管穿孔,接受了1个月的开放引流。所有患者均治愈,无感染复发。

结论

对于颈椎前路减压融合术后早期深部SSI,手术清创有效根除感染。但对于诊断延误的病例,前路清创并预防性取出植入物及后路重建是理想选择。应注意并避免食管穿孔合并多次清创的情况。

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