一名骨骼未成熟女孩的胸椎骨巨细胞瘤。病例报告及文献综述。
A thoracic spinal bone giant cell tumor in a skeletally immature girl. A case report and literature review.
作者信息
Sigwalt Loic, Bourgeois Emeline, Eid Ahmad, Durand Chantal, Griffet Jacques, Courvoisier Aurélien
机构信息
Department of Paediatric Orthopedic Surgery, Hopital Couple Enfants, Grenoble Alpes University, Grenoble, France.
Department of Paediatric Radiology, Hopital Couple Enfants, Grenoble Alpes University, Grenoble, France.
出版信息
Childs Nerv Syst. 2016 May;32(5):873-6. doi: 10.1007/s00381-015-2991-0. Epub 2016 Jan 5.
PURPOSE
Giant cell tumors (GCT) are benign primary bone tumors, locally aggressive, affecting in long bones in young adults during the third decade. It is rare to experience this lesion in skeletally immature patients. GCT are related to a risk of local recurrence and malignant transformation.
METHOD
We report a rare case of a giant cell tumor of the thoracic spine in a skeletally immature girl presenting with a painful right scoliosis.
RESULTS
MRI, CT scan, and bone scintigraphy were discordant and the percutaneous biopsy non-contributive.
CONCLUSION
A marginal "en bloc" resection was performed and revealed the GCT. Based on a literature review, the diagnosis and the surgical management of this case are discussed.
目的
骨巨细胞瘤（GCT）是一种良性原发性骨肿瘤，具有局部侵袭性，好发于年轻成年人第三个十年的长骨。在骨骼未成熟的患者中发生这种病变较为罕见。骨巨细胞瘤存在局部复发和恶变的风险。
方法
我们报告了一例罕见的骨骼未成熟女孩胸椎骨巨细胞瘤病例，该女孩表现为右侧疼痛性脊柱侧弯。
结果
磁共振成像（MRI）、计算机断层扫描（CT）和骨闪烁显像结果不一致，经皮活检未提供有效信息。
结论
进行了边缘性“整块”切除，病理显示为骨巨细胞瘤。基于文献综述，对该病例的诊断和手术治疗进行了讨论。
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