痔切除标本中提示乳头瘤病毒的组织学表现之间的关联。
ASSOCIATION AMONG HISTOLOGICAL FINDINGS SUGGESTIVE OF PAPILLOMA VIRUS ON HEMORRHOIDECTOMY SPECIMENS.
作者信息
da Silva Soraya Souto, Nakajima Gerson Suguiyama, Guimarães Ricardo Alexandre, Mourão Flávia da Costa
机构信息
Getúlio Vargas University Hospital, Federal University of Amazonas, Manaus, AM, Brazil.
出版信息
Arq Bras Cir Dig. 2015 Nov-Dec;28(4):255-7. doi: 10.1590/S0102-6720201500040009.
BACKGROUND
Many researchers studied human Papillomavirus infection in the anal area supposing it represents a risk factor for precursor lesions of anal cancer.
AIM
To study the association between histological findings suggestive of injury by the virus in hemorrhoidectomy specimens.
METHOD
Prevalence study was carried out based on histopathological analysis of hemorrhoidectomy specimens to find viral cytopathic effects. These findings were compared with anal condyloma acuminata that had no relationship with hemorrhoidectomy for microscopic comparison.
RESULTS
Of the 91 hemorroidectomies analyzed, eight had findings suggestive of viral cytopathic effects, with the presence of irregular acanthosis in 63%, koilocytes in 50% and other indirect viral cytopathic effects, such as hyperkeratosis (38%), parakeratosis (25% ) and papillomatosis (13%).
CONCLUSION
This study was unable to conclude that there is an association between these two pathologic entities.
背景
许多研究人员对肛门区域的人乳头瘤病毒感染进行了研究，认为它是肛门癌前驱病变的一个危险因素。
目的
研究痔切除标本中提示病毒损伤的组织学发现之间的关联。
方法
基于对痔切除标本的组织病理学分析进行患病率研究，以发现病毒细胞病变效应。将这些发现与与痔切除术无关的肛门尖锐湿疣进行微观比较。
结果
在分析的91例痔切除术中，8例有提示病毒细胞病变效应的发现，63%存在不规则棘皮症，50%存在空泡细胞，以及其他间接病毒细胞病变效应，如角化过度（38%）、不全角化（25%）和乳头瘤病（13%）。
结论
本研究无法得出这两种病理实体之间存在关联的结论。
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