Yuan Shi-Min
The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Putian, China.
Braz J Cardiovasc Surg. 2015 Sep-Oct;30(5):571-8. doi: 10.5935/1678-9741.20140112.
This study aims to present an updated clinical picture of the infected cardiac myxoma. Revankar & Clark made a systematic review of infected cardiac myxoma based on the literature before 1998. Since then, there has not been any updated information describing its recent changing trends.
A comprehensive literature search of infected cardiac myxoma was conducted on MEDLINE, Highwire Press and Google between 1998 and 2014.
In comparison with Revankar & Clark's series, the present series disclosed a significantly decreased overall mortality. It is believed that refinement of the prompt diagnosis and timely management (use of sensitive antibiotics and surgical resection of the infected myxoma) have resulted in better outcomes of such patients.
The present series of infected cardiac myxoma illustrated some aggravated clinical manifestations (relative more occasions of high-grade fever, multiple embolic events and the presence of refractory microorganisms), which should draw enough attention to careful diagnosis and treatment. In general, the prognosis of infected cardiac myxoma is relatively benign and the long-term survival is always promising.
本研究旨在呈现感染性心脏黏液瘤的最新临床情况。Revankar和Clark基于1998年以前的文献对感染性心脏黏液瘤进行了系统综述。自那时起,尚无描述其近期变化趋势的更新信息。
1998年至2014年间,在医学文献数据库(MEDLINE)、Highwire Press和谷歌上对感染性心脏黏液瘤进行了全面的文献检索。
与Revankar和Clark的系列研究相比,本系列研究显示总体死亡率显著降低。据信,及时诊断的改进和及时治疗(使用敏感抗生素及手术切除感染的黏液瘤)使此类患者有了更好的治疗结果。
本系列感染性心脏黏液瘤显示出一些加重的临床表现(相对更多的高热情况、多次栓塞事件以及存在难治性微生物),这应引起对仔细诊断和治疗的足够重视。总体而言,感染性心脏黏液瘤的预后相对良好,长期生存前景乐观。