Weiner Scott G, Horton Laura C, Green Traci C, Butler Stephen F
Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, United States.
Tufts University School of Medicine, Boston, MA, United States.
Drug Alcohol Depend. 2016 Feb 1;159:152-7. doi: 10.1016/j.drugalcdep.2015.12.007. Epub 2015 Dec 21.
This study aimed to: (a) determine the percentage of ED patients receiving prescriptions for opioid pain medications that meet the criteria for "high-risk for abuse potential" on the Screener and Opioid Assessment for Patients with Pain (SOAPP(®)-R), (b) determine the percentage of patients with high-risk behavior on the state prescription drug monitoring program (PDMP) database, (c) compare the SOAPP-R with data from the PDMP, and (d) determine psychometric properties of SOAPP-R for ED patients
Convenience sample of ED patients who were being considered for discharge with a prescription for an opioid pain medication. Subjects completed SOAPP-R on an electronic tablet and PDMP data was obtained. Scores on SOAPP-R ≥ 18 were defined as "at-risk", and PDMP data showing both ≥ 4 opioid prescriptions and ≥ 4 providers in 12 months was considered the criterion standard for high-risk behavior.
82 patients (88.2%) provided consent. 32.9% (n=27) were determined to be "at-risk" (score ≥ 18) by SOAPP-R. 15.9% (n=13) subjects met PDMP criteria and 53.9% (n=7) of those had SOAPP-R scores ≥ 18 (sensitivity 54%, specificity 71%, positive predictive value 26%, negative predictive value 89%). The association of an at-risk SOAPP-R score and PDMP high-risk criteria was an adjusted odds ratio of 1.39 (95% confidence interval 0.73-3.68).
In our population, about one-third of patients being considered for discharge with an opioid prescription scored "at-risk" on SOAPP-R and 15.9% met the PDMP high-risk criteria. The high negative predictive value of SOAPP-R indicates it may be a useful screening tool for the ED patient population.
本研究旨在:(a) 确定急诊患者中开具符合疼痛患者筛查与阿片类药物评估(SOAPP(®)-R)“潜在滥用高风险”标准的阿片类镇痛药物处方的比例;(b) 确定州处方药监测计划(PDMP)数据库中具有高风险行为的患者比例;(c) 将SOAPP-R与PDMP数据进行比较;(d) 确定SOAPP-R在急诊患者中的心理测量特性。
对考虑开具阿片类镇痛药物处方出院的急诊患者进行便利抽样。受试者在电子平板电脑上完成SOAPP-R,并获取PDMP数据。SOAPP-R得分≥18被定义为“有风险”,PDMP数据显示在12个月内有≥4张阿片类药物处方且≥4名开处方者被视为高风险行为的标准。
82名患者(88.2%)提供了同意。SOAPP-R确定32.9%(n = 27)为“有风险”(得分≥18)。15.9%(n = 13)的受试者符合PDMP标准,其中53.9%(n = 7)的SOAPP-R得分≥18(敏感性54%,特异性71%,阳性预测值26%,阴性预测值89%)。有风险的SOAPP-R得分与PDMP高风险标准的关联调整比值比为1.39(95%置信区间0.73 - 3.68)。
在我们的研究人群中,约三分之一考虑开具阿片类药物处方出院的患者在SOAPP-R上得分“有风险”,15.9%符合PDMP高风险标准。SOAPP-R的高阴性预测值表明它可能是急诊患者群体的一种有用筛查工具。