Al-Fahdawi Mahmood Abd, Farid Mary Medhat, El-Fotouh Mona Abou, El-Kassaby Marwa Abdelwahab
Cleft Palate Craniofac J. 2017 Mar;54(2):202-209. doi: 10.1597/15-134. Epub 2016 Jan 11.
OBJECTIVE: To assess the nasopharyngeal airway volume, cross-sectional area, and depth in previously repaired nonsyndromic unilateral cleft lip and palate versus bilateral cleft lip and palate patients compared with noncleft controls using cone-beam computed tomography with the ultimate goal of finding whether cleft lip and palate patients are more liable to nasopharyngeal airway obstruction. DESIGN: A retrospective analysis comparing bilateral cleft lip and palate, unilateral cleft lip and palate, and control subjects. Significance at P ≤ .05. SETTING: Cleft Care Center and the outpatient clinic that are both affiliated with our faculty. PARTICIPANTS: Cone-beam computed tomography data were selected of 58 individuals aged 9 to 12 years: 14 with bilateral cleft lip and palate and 20 with unilateral cleft lip and palate as well as 24 age- and gender-matched noncleft controls. VARIABLES: Volume, depth, and cross-sectional area of nasopharyngeal airway were measured. RESULTS: Patients with bilateral cleft lip and palate showed significantly larger nasopharyngeal airway volume than controls and patients with unilateral cleft lip and palate (P < .001). Patients with bilateral cleft lip and palate showed significantly larger cross-sectional area than those with unilateral cleft lip and palate (P < .001) and insignificant cross-sectional area compared with controls (P > .05). Patients with bilateral cleft lip and palate showed significantly larger depth than controls and those with unilateral cleft lip and palate (P < .001). Patients with unilateral cleft lip and palate showed insignificant nasopharyngeal airway volume, cross-sectional area, and depth compared with controls (P > .05). CONCLUSIONS: Unilateral and bilateral cleft lip and palate patients did not show significantly less volume, cross-sectional area, or depth of nasopharyngeal airway than controls. From the results of this study we conclude that unilateral and bilateral cleft lip and palate patients at the studied age and stage of repaired clefts are not more prone to nasopharyngeal airway obstruction than controls.
目的：使用锥形束计算机断层扫描技术，评估既往接受过修复手术的非综合征性单侧唇腭裂和双侧唇腭裂患者的鼻咽气道容积、横截面积和深度，并与非腭裂对照组进行比较，最终目的是确定唇腭裂患者是否更易发生鼻咽气道阻塞。 设计：一项比较双侧唇腭裂、单侧唇腭裂和对照组的回顾性分析。P≤0.05具有统计学意义。 地点：隶属于我们学院的腭裂护理中心和门诊诊所。 参与者：选取了58名9至12岁个体的锥形束计算机断层扫描数据：14例双侧唇腭裂患者、20例单侧唇腭裂患者以及24例年龄和性别匹配的非腭裂对照者。 变量：测量鼻咽气道的容积、深度和横截面积。 结果：双侧唇腭裂患者的鼻咽气道容积显著大于对照组和单侧唇腭裂患者（P<0.001）。双侧唇腭裂患者的横截面积显著大于单侧唇腭裂患者（P<0.001），与对照组相比无显著差异（P>0.05）。双侧唇腭裂患者的深度显著大于对照组和单侧唇腭裂患者（P<0.001）。与对照组相比，单侧唇腭裂患者的鼻咽气道容积、横截面积和深度无显著差异（P>0.05）。 结论：单侧和双侧唇腭裂患者的鼻咽气道容积、横截面积或深度并不显著小于对照组。从本研究结果我们得出结论，在所研究的年龄和腭裂修复阶段，单侧和双侧唇腭裂患者并不比对照组更易发生鼻咽气道阻塞。
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