Hu Jiong, Chen Zhe, Cao Yan-guang, Wei Jia-sen
Zhongguo Gu Shang. 2015 Nov;28(11):982-7.
To explore the clinical effects of Dynesys system combined with posterior lumbar interbody fusion (PLIF) in treating multiple lumbar degenerative disease.
The clinical data of 46 patients with multiple lumbar degenerative diseases treated by Dynesys system combined with PLIF from September 2010 to May 2013 were retrospectively analyzed. There were 17 males and 29 females, aged from 38 to 68 years old with an average of (56.38±11.63) years. Operation section was in L2-L5 of 16 patients (6 with fusion of L4,5 and 10 with fusion of L4,5,L5S1) and in L3-S1 of 30 patients (11 with fusion of L5S1 and 19 with fusion of L4,5,L5S1). Patients were followed up for three times: postoperative 3 months, 1 year and final follow-up. Visual analogue scale (VAS) and Oswestry Disability Index (ODI) were used to assess clinical symptoms preoperatively and postoperatively. All patients underwent flexion/extension radiographs examinations before surgery and at final follow-up. Range of motion (ROM) and disc height index (DHI) were recorded.
All patients were followed up from 16 to 48 months with the mean of (23.23±7.34) months. At third follow-up after operation, ODI and VAS of lumbago and leg pain were significant improved than that of preoperative (P<0.01). DHI of fusion segment was significantly increased than that of preoperative (P<0.05). There was no significant difference in adjacent non-fusion segment between preoperative and postoperative (P>0.05). Postoperative ROM of fusion and non-fusion segments were obviously decreased than that of preoperative. There was no significant difference in ROM of upper adjacent non-fusion segment between 3 months and 1 year after operation (P>0.05), but at final follow-up, the ROM was increased (P<0.05).
The preliminary clinical results of the Dynesys system combined with PLIF in the treatment of multiple lumbar degenerative diseases are satisfactory. It can be determined in fusion or non-fusion according to the individual needs and can reserve the some intervertebral motion, prevent the early degeneration of adjacent segments. However, its long-term clinical efficacy should be verified with long time.
探讨Dynesys系统联合后路腰椎椎间融合术(PLIF)治疗多节段腰椎退变疾病的临床效果。
回顾性分析2010年9月至2013年5月采用Dynesys系统联合PLIF治疗的46例多节段腰椎退变疾病患者的临床资料。其中男17例,女29例,年龄38~68岁,平均(56.38±11.63)岁。手术节段为L2-L5共16例(L4、5融合6例,L4、5、L5S1融合10例),L3-S1共30例(L5S1融合11例,L4、5、L5S1融合19例)。对患者进行3次随访:术后3个月、1年及末次随访。采用视觉模拟评分法(VAS)和Oswestry功能障碍指数(ODI)评估术前及术后临床症状。所有患者在手术前及末次随访时均行腰椎前屈/后伸位X线片检查,记录活动度(ROM)和椎间盘高度指数(DHI)。
所有患者随访16~48个月,平均(23.23±7.34)个月。术后第3次随访时,ODI及腰腿痛VAS较术前显著改善(P<0.01)。融合节段DHI较术前显著增加(P<0.05)。相邻非融合节段术前与术后比较差异无统计学意义(P>0.05)。术后融合节段及非融合节段ROM均较术前明显减小。术后3个月与1年时上相邻非融合节段ROM比较差异无统计学意义(P>0.05),但末次随访时ROM增加(P<0.05)。
Dynesys系统联合PLIF治疗多节段腰椎退变疾病的初步临床效果满意。可根据个体需求决定融合与否,能保留一定的椎间活动度,预防相邻节段早期退变。但其长期临床疗效尚需长期验证。