Fan Wenting, Zhu Jiaan, Li Jianguo, Zhang Wanlei, Li Chun
Department of Ultrasound, Peking University People's Hospital, Beijing, China -
Int Angiol. 2016 Dec;35(6):586-592. Epub 2016 Jan 14.
The aims of this study were to examine ultrasound morphological changes in the carotid wall in cases of Takayasu's arteritis and to thereby determine the value of ultrasound for assessments of Takayasu's arteritis disease activity and follow-up studies.
We used high-frequency ultrasound to analyze morphological changes in 51 Takayasu's arteritis patients and compared the findings with clinical and laboratory parameters. A follow-up study of 20 patients was performed.
Five types of ultrasonographic images were observed in the carotid walls of Takayasu's arteritis patients. Type III and type IV images were observed in younger patients; smaller wall thicknesses and less luminal stenosis were observed in these images. Type II and type IV images were more frequently obtained in cases involving active patients, whereas type I and type III images were more often acquired in cases involving inactive patients with significantly lower Indian Takayasu clinical activity scores. During follow-up, the wall thickness and outer diameter of the carotid increased in patients who relapsed and decreased in patients who remained in remission.
The five types of carotid ultrasound images reveal Takayasu's arteritis-related morphological changes in the vessel wall, which reflect anatomical changes. Carotid ultrasound should play a central role in monitoring the progression of Takayasu's arteritis.
本研究旨在探讨大动脉炎患者颈动脉壁的超声形态学变化，从而确定超声在大动脉炎疾病活动评估及随访研究中的价值。
我们使用高频超声分析了51例大动脉炎患者的形态学变化，并将结果与临床和实验室参数进行了比较。对20例患者进行了随访研究。
在大动脉炎患者的颈动脉壁中观察到五种超声图像类型。III型和IV型图像见于较年轻患者；这些图像中观察到的壁厚度较小且管腔狭窄较轻。II型和IV型图像在活动期患者中更常见，而I型和III型图像在印度大动脉炎临床活动评分显著较低的非活动期患者中更常出现。随访期间，复发患者的颈动脉壁厚度和外径增加，缓解患者的则减少。
五种类型的颈动脉超声图像揭示了大动脉炎相关的血管壁形态学变化，反映了解剖学改变。颈动脉超声应在监测大动脉炎的进展中发挥核心作用。
