Gao Chao, Zhang Yong, Jing Ming, Qu Wei, Li Jia, Zhao Xiang-Rong, Yu Yong-Hua
From the Radiation Oncology Ward 2, Shandong Cancer Hospital and Institute (CG, YZ, WQ, JL, X-RZ, Y-HY); School of Medical and Life Sciences, Shandong Academy of Medical Sciences, Jinan University (CG, X-RZ); and Department of Dermatology, JiNan Dermatosis Prevention and Control Hospital, Jinan, Shandong, China (MJ).
Medicine (Baltimore). 2016 Jan;95(2):e2433. doi: 10.1097/MD.0000000000002433.
Solitary fibrous tumor of the pelvic is an uncommon neoplasm with nonspecific symptoms. Reports of malignant transformation are especially rare. We report a case of solitary fibrous tumor in pelvic. A unique feature of our case compared with previously reported is that this patient relapsed with malignant transformation and had significant response to radiotherapy. The patient was initially treated with surgery, followed by postoperative dimensional conformal intensity modulated radiation therapy (dynamic MLC VRIAN 23EX Linac, inversely optimized by the Eclipse system) to provide a radical cure for residual tumor.In this case, there were no signs of recurrence after six and a half years of further follow-up, indicating that postoperation radiotherapy may be an effective treatment for SFT with malignant transformation in pelvic.
盆腔孤立性纤维瘤是一种具有非特异性症状的罕见肿瘤。恶性转化的报道尤为罕见。我们报告一例盆腔孤立性纤维瘤病例。与先前报道相比,我们病例的一个独特特征是该患者出现恶性转化复发且对放疗有显著反应。患者最初接受手术治疗,随后进行术后三维适形调强放射治疗(使用动态多叶准直器的瓦里安23EX直线加速器,由Eclipse系统进行逆向优化)以根治残留肿瘤。在该病例中,经过六年半的进一步随访没有复发迹象,表明术后放疗可能是盆腔恶性转化孤立性纤维瘤的一种有效治疗方法。