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腹腔镜切除膈肌肿瘤结节治疗复发性子宫内膜癌

Laparoscopic Resection of the Diaphragmatic Tumor Nodule for Management of Recurrent Endometrial Cancer.

作者信息

Menderes Gulden, Schwab Carlton, Black Jonathan, Silasi Dan-Arin

机构信息

Department of Obstetrics, Gynecology, and Reproductive Sciences, Section of Gynecologic Oncology, Yale University School of Medicine, New Haven, Connecticut.

Department of Obstetrics, Gynecology, and Reproductive Sciences, Section of Gynecologic Oncology, Yale University School of Medicine, New Haven, Connecticut.

出版信息

J Minim Invasive Gynecol. 2016 May-Jun;23(4):473-4. doi: 10.1016/j.jmig.2016.01.006. Epub 2016 Jan 8.

Abstract

STUDY OBJECTIVE

To show a surgical video in which an isolated hemidiaphragmatic tumor nodule was resected laparoscopically in a patient with isolated recurrence of endometrial cancer.

DESIGN

Case report (Canadian Task Force Classification study design III).

SETTING

Tertiary referral center in New Haven, CT.

INTERVENTIONS

This is a step-by-step illustration of tumor nodule resection from the right hemidiaphragm. The patient was a 55-year-old white woman who was diagnosed with stage IIIA endometrioid endometrial adenocarcinoma in June 2011 after surgical debulking. She received adjuvant carboplatin and paclitaxel and vaginal brachytherapy. She was disease free until March 2015 when she presented with right upper abdominal pain. A computed tomographic scan showed a 1-cm implant on the right hepatic dome. The implant was noted to be enlarged to 1.8 cm on a subsequent computed tomographic scan in August 2015. The patient was taken to the operating room for exploratory laparoscopy and resection of the hepatic dome/hemidiaphragmatic tumor nodule. The tumor nodule was noted to involve the full thickness of the right hemidiaphragm. The resection of the entire nodule required perforation of the diaphragm, which was reapproximated after the excision.

MAIN RESULTS

The procedure was performed without any complications. The patient had an uneventful postoperative course and was discharged home on postoperative day 1. Pathology revealed metastatic endometrioid endometrial adenocarcinoma with negative resection margins.

CONCLUSION

Laparoscopic resection of the diaphragmatic tumor nodule and the reapproximation of the diaphragm were successfully performed in this patient with isolated disease recurrence. The laparoscopic approach should be considered for management of isolated recurrences in gynecologic cancers by experienced laparoscopic surgeons because it might otherwise be associated with significant morbidity and mortality [1-3].

摘要

研究目的

展示一段手术视频,该视频记录了一名子宫内膜癌孤立复发患者的腹腔镜下孤立性半膈肌肿瘤结节切除术。

设计

病例报告(加拿大工作组分类研究设计III)。

地点

康涅狄格州纽黑文的三级转诊中心。

干预措施

这是一份从右半膈肌切除肿瘤结节的分步说明。患者为一名55岁白人女性,2011年6月在手术减瘤后被诊断为IIIA期子宫内膜样子宫内膜腺癌。她接受了辅助性卡铂和紫杉醇治疗以及阴道近距离放疗。直到2015年3月她出现右上腹疼痛之前,病情一直无复发。计算机断层扫描显示右肝穹窿有一个1厘米的植入物。在2015年8月的后续计算机断层扫描中,该植入物增大至1.8厘米。患者被送往手术室进行 exploratory laparoscopy(此处原文有误,推测可能是“exploratory laparotomy”,即剖腹探查术)以及肝穹窿/半膈肌肿瘤结节切除术。肿瘤结节累及右半膈肌全层。切除整个结节需要穿透膈肌,切除后将膈肌重新对合。

主要结果

手术过程未出现任何并发症。患者术后恢复顺利,术后第1天出院。病理显示为转移性子宫内膜样子宫内膜腺癌,切缘阴性。

结论

该孤立性疾病复发患者成功进行了腹腔镜下膈肌肿瘤结节切除术及膈肌重新对合术。对于妇科癌症孤立复发的治疗,经验丰富的腹腔镜外科医生应考虑采用腹腔镜方法,因为否则可能会导致显著的发病率和死亡率[1 - 3]。

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