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阻塞性睡眠呼吸暂停患者翼钩长度与呼吸暂停低通气指数的相关性:三维锥形束计算机断层扫描与多导睡眠图联合研究

Association between pterygoid hamulus length and apnea hypopnea index in patients with obstructive sleep apnea: a combined three-dimensional cone beam computed tomography and polysomnographic study.

作者信息

Oz Ulas, Orhan Kaan, Aksoy Secil, Ciftci Fatma, Özdoğanoğlu Tunis, Rasmussen Finn

机构信息

Department of Orthodontics, School of Dentistry, Near East University, Nicosia, Northern Cyprus.

Department of Dento-Maxillo-Facial Radiology, Ankara University, Ankara, Turkey.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Mar;121(3):330-9. doi: 10.1016/j.oooo.2015.10.032. Epub 2015 Nov 14.

Abstract

OBJECTIVE

The purpose of this study was to investigate the relationships among the pterygoid hamulus (PH), the maxillo-mandibular complex to the pharynx, the upper airway, and the soft palate and a possible connection to sleep apnea severity as assessed by polysomnography.

STUDY DESIGN

A total of 100 left and right sides of the PH were retrospectively measured by two observers from 50 cone beam computed tomography images by using three-dimensional rendering program in patients with obstructive sleep apnea (33 males and 17 females, with a mean age of 56.8 years; range 32-82 years).

RESULTS

The mean apnea hypopnea index was 30.2 (range 0-95). A linear regression analysis on the apnea hypopnea index with the total length of the PH adjusted for gender, body mass index, neck circumference, and age showed a statistically significant association: (-0.234(∗); P = .005). None of the other variables reached formal significance.

CONCLUSION

The pterygoid hamulus length is inversely associated with sleep apnea severity. Our study provides further insight into the pathophysiology of sleep apnea, with the result that PH length could be a future supplementary measurement to help clinicians to stratify and determine the best treatment options for patients with obstructive sleep apnea.

摘要

目的

本研究旨在探讨翼钩(PH)、上颌下颌复合体与咽部、上气道及软腭之间的关系,以及通过多导睡眠图评估的与睡眠呼吸暂停严重程度的可能联系。

研究设计

使用三维重建程序,两名观察者从50例阻塞性睡眠呼吸暂停患者(33例男性和17例女性,平均年龄56.8岁;范围32 - 82岁)的锥形束计算机断层扫描图像中,对100个左右侧的翼钩进行回顾性测量。

结果

平均呼吸暂停低通气指数为30.2(范围0 - 95)。对呼吸暂停低通气指数与经性别、体重指数、颈围和年龄调整后的翼钩总长度进行线性回归分析,显示出统计学上的显著关联:(-0.234(∗);P = 0.005)。其他变量均未达到显著意义。

结论

翼钩长度与睡眠呼吸暂停严重程度呈负相关。我们的研究为睡眠呼吸暂停的病理生理学提供了进一步的见解,结果表明翼钩长度可能成为未来的一项辅助测量指标,以帮助临床医生对阻塞性睡眠呼吸暂停患者进行分层并确定最佳治疗方案。

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