Nassali Mercy Nkuba, Benti Tadele Melese, Bandani-Ntsabele Moreri, Musinguzi Elly
Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Botswana, Private Bag 00713, Gaborone, Botswana.
Department of Obstetrics and Gynaecology, Princess Marina Hospital, P.O. Box 258, Gaborone, Botswana.
BMC Res Notes. 2016 Jan 19;9:31. doi: 10.1186/s13104-016-1844-6.
Despite advances in diagnostic imaging and focused antenatal care, cases of undiagnosed abdominal pregnancies at term are still reported in obstetric practice. It is atypical and very rare for a patient to be asymptomatic late in pregnancy and for the pregnancy to result in a live birth with no evidence of intrauterine growth restriction despite the unfavourable implantation site. This late term asymptomatic presentation despite routine antenatal care demonstrates a diagnostic challenge.
We report a case of a 26 year old Primigravida with an asymptomatic and undiagnosed abdominal pregnancy carried beyond 41 weeks of gestation espite routine antenatal care and serial ultrasound reports. She presented for a routine antenatal care visit at 41 weeks of gestation. Induction of labour was initiated due to the late term gestation but was unsuccessful. At this point the fetus developed severe tachycardia and CTG confirmed persistent non-reassuring foetal heart rate patterns. The mother was then prepared for an emergency caesarean delivery. Abdominal pregnancy was only diagnosed at laparotomy where a term male baby weighing 3108 g was delivered with an Apgar Score of 7 and 8 at 1 and 5 min respectively. The placenta which was implanted into the omentum, ileal mesentery and extending to the pouch of Douglas was removed following active bleeding from its detached margins. She was transfused with two units of blood and four units of fresh frozen plasma. Postoperative morbidity was minimal with transient paralytic ileus on the second post-operative day. Her recovery was otherwise uneventful and she was discharged on the seventh post-operative day in good condition. The neonate developed meconium aspiration syndrome and passed away on the 2nd day of life despite having undergone standard care. A post-mortem examination was not performed because the family did not consent to the procedure. Follow up of the mother at 2, 6 weeks and 6 months postpartum was uneventful.
This atypical presentation of an asymptomatic abdominal pregnancy carried tolate term and only diagnosed at laparotomy despite routine antenatal care demonstrates a significant lapse in diagnosis. Clinicians and radiologists must always bear this possibility in mind during routine client evaluation. Skills training in Obstetric ultrasound and in the clinical assessment of obstetric patients should emphasize features suggestive of abdominal pregnancy. This will improve diagnosis, ensure appropriate management and minimise complications. Immediate termination of pregnancy can be offered if the diagnosis is made before 20 weeks of gestation. Patients diagnosed with advanced abdominal pregnancies and are stable can be monitored under close surveillance and delivered at 34 weeks of gestation after lung maturity is achieved. Although removal of the placenta carries a higher risk of haemorrhage, a partially detached placenta can be delivered with minimal morbidity and a good maternal outcome. Given the documented low survival rates of neonates in such cases, neonatal units must be adequately equipped and staffed to support them. Post-mortem examination is important to confirm cause of death and exclude other complications and congenital anomalies. Communities need to be educated about the importance of this procedure.
尽管诊断性影像学和重点产前护理取得了进展,但产科实践中仍有足月未诊断出的腹腔妊娠病例报告。在妊娠晚期患者无症状,且尽管着床部位不利但妊娠仍能顺产且无宫内生长受限迹象,这种情况既不典型也非常罕见。尽管进行了常规产前护理,但这种晚期无症状表现仍显示出诊断上的挑战。
我们报告一例26岁初产妇,尽管进行了常规产前护理并多次进行超声检查,但她的腹腔妊娠无症状且未被诊断出来,妊娠超过了41周。她在妊娠41周时前来进行常规产前检查。由于孕周已达晚期,开始引产,但未成功。此时胎儿出现严重心动过速,CTG证实胎儿心率持续异常。随后为母亲准备进行急诊剖宫产。直到剖腹手术时才诊断出腹腔妊娠,术中娩出一名足月男婴,体重3108克,1分钟和5分钟时的阿氏评分分别为7分和8分。植入大网膜、回肠系膜并延伸至Douglas陷凹的胎盘,在其分离边缘出现活动性出血后被切除。她输注了两单位血液和四单位新鲜冰冻血浆。术后并发症轻微,术后第二天出现短暂性麻痹性肠梗阻。她的恢复情况良好,术后第七天出院。新生儿出现胎粪吸入综合征,尽管接受了标准治疗,但在出生第二天死亡。由于家属不同意,未进行尸检。产后2周、6周和6个月对母亲进行随访,情况均正常。
这种无症状腹腔妊娠晚期才出现且尽管进行了常规产前护理直到剖腹手术时才被诊断出来的非典型表现,显示出诊断上的重大失误。临床医生和放射科医生在对患者进行常规评估时必须始终牢记这种可能性。产科超声技能培训以及产科患者的临床评估应强调提示腹腔妊娠的特征。这将改善诊断、确保适当管理并使并发症最小化。如果在妊娠20周前做出诊断,可以立即终止妊娠。诊断为晚期腹腔妊娠且情况稳定的患者,可以在严密监测下进行观察,在肺成熟后于34周分娩。尽管胎盘剥离有较高的出血风险,但部分剥离的胎盘可以以较低的发病率娩出,产妇预后良好。鉴于此类病例中新生儿的存活率较低,新生儿病房必须配备充足的设备和人员以支持他们。尸检对于确认死亡原因并排除其他并发症和先天性异常很重要。需要对社区进行关于该程序重要性的教育。