Agarwal Shikhar, Sud Karan, Menon Venu
Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH (S.A., K.S., V.M.).
J Am Heart Assoc. 2016 Jan 19;5(1):e002330. doi: 10.1161/JAHA.115.002330.
We aimed to assess trends in hospitalization, outcomes, and resource utilization among patients admitted with adult congenital heart disease (ACHD).
We used the 2003-2012 US Nationwide Inpatient Sample for this study. All admissions with an ACHD were identified using standard ICD codes. Resource utilization was assessed using length of stay, invasive procedure utilization, and cost of hospitalization. There was a significant increase in the number of both simple (101%) as well as complex congenital heart disease (53%)-related admissions across 2003-2012. In addition, there was a considerable increase in the prevalence of traditional cardiovascular risk factors including older age, along with a higher prevalence of hypertension, diabetes, smoking, obesity, chronic kidney disease, and peripheral arterial disease. Besides miscellaneous causes, congestive heart failure (11.8%), valve disease (15.5%), and cerebrovascular accident (26.1%) were the top causes of admission to the hospital among patients with complex ACHD, simple ACHD without atrial septal defects/patent foramen ovale and simple atrial septal defects/patent foramen ovale patients, respectively. In-hospital mortality has been relatively constant among patients with complex ACHD as well as simple ACHD without atrial septal defects/patent foramen ovale. However, there has been considerable increase in the average length of stay and cost of hospitalization among the ACHD patients during 2003-2012.
There has been a progressive increase in ACHD admissions across 2003-2012 in the United States, with increasing healthcare resource utilization among these patients. Moreover, there has been a change in the cardiovascular comorbidities of these patients, adding a layer of complexity in management of ACHD patients.
我们旨在评估成人先天性心脏病(ACHD)患者的住院情况、治疗结果及资源利用趋势。
本研究使用了2003 - 2012年美国全国住院患者样本。通过标准ICD编码识别所有ACHD入院病例。利用住院时长、侵入性操作使用情况及住院费用评估资源利用情况。2003 - 2012年间,单纯先天性心脏病(增长101%)及复杂先天性心脏病(增长53%)相关入院病例数量均显著增加。此外,包括高龄在内的传统心血管危险因素患病率显著上升,同时高血压、糖尿病、吸烟、肥胖、慢性肾病及外周动脉疾病的患病率也更高。除其他各种原因外,充血性心力衰竭(11.8%)、瓣膜疾病(15.5%)及脑血管意外(26.1%)分别是复杂ACHD患者、无房间隔缺损/卵圆孔未闭的单纯ACHD患者及房间隔缺损/卵圆孔未闭患者入院的主要原因。复杂ACHD患者以及无房间隔缺损/卵圆孔未闭的单纯ACHD患者的院内死亡率相对稳定。然而,2003 - 2012年间ACHD患者的平均住院时长及住院费用显著增加。
2003 - 2012年间美国ACHD入院病例数呈逐步上升趋势,这些患者的医疗资源利用也在增加。此外,这些患者的心血管合并症发生了变化,给ACHD患者的管理增加了一层复杂性。