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厄瓜多尔单胎妊娠合并子痫前期和子痫的围产期结局

Perinatal outcome in singleton pregnancies complicated with preeclampsia and eclampsia in Ecuador.

作者信息

Phoa K Y N, Chedraui P, Pérez-López F R, Wendte J F, Ghiabi S, Vrijkotte T, Pinto P

机构信息

a Academic Medical Centre Amsterdam , University of Amsterdam , Amsterdam , the Netherlands .

b High Risk Pregnancy Labor and Delivery Unit , Enrique C. Sotomayor Obstetrics and Gynecology Hospital , Guayaquil , Ecuador .

出版信息

J Obstet Gynaecol. 2016 Jul;36(5):581-4. doi: 10.3109/01443615.2015.1107532. Epub 2016 Jan 20.

Abstract

Preeclampsia in Ecuador is an understudied subject since available epidemiological data are scarce. The aim of this study was to describe perinatal outcomes among singleton pregnancies complicated with preeclampsia and eclampsia in a sample of low-income Ecuadorian women. Pregnant women complicated with preeclampsia (mild and severe) and eclampsia (defined according to criteria of the ACOG) delivering at the Enrique C. Sotomayor Obstetrics and Gynecology Hospital, Guayaquil, Ecuador were surveyed with a structured questionnaire containing maternal (socio-demographic) and neonatal data. Perinatal outcomes were compared according to severity of clinical presentation. A total of 163 women with preeclampsia [mild (23.9%), severe (68.7%) and eclampsia (7.4%)] were surveyed. Perinatal mortality and stillbirth rate was similar among studied groups (mild vs. severe preeclampsia/eclampsia cases). However, severe cases displayed higher rates of adverse perinatal outcomes: lower birth Apgar scores, more preterm births, and more low birth weight and small for gestational age infants. Caesarean-section rate and the number of admissions to intensive or intermediate neonatal care were higher in severe cases. A similar trend was found when analysis excluded preterm gestations. In conclusion, in this specific low-income Ecuadorian population perinatal outcome was adverse in pregnancies complicated with severe preeclampsia/eclampsia.

摘要

由于现有流行病学数据匮乏,厄瓜多尔的子痫前期仍是一个研究不足的课题。本研究旨在描述厄瓜多尔低收入妇女样本中,单胎妊娠合并子痫前期和子痫的围产期结局。对在厄瓜多尔瓜亚基尔市恩里克·C·索托马约尔妇产科医院分娩的合并子痫前期(轻度和重度)和子痫(根据美国妇产科医师学会标准定义)的孕妇,采用包含产妇(社会人口统计学)和新生儿数据的结构化问卷进行调查。根据临床表现的严重程度比较围产期结局。共调查了163名单胎妊娠合并子痫前期的妇女[轻度(23.9%)、重度(68.7%)和子痫(7.4%)]。研究组(轻度子痫前期/子痫与重度子痫前期/子痫病例)的围产期死亡率和死产率相似。然而,重度病例显示出更高的不良围产期结局发生率:出生时阿氏评分较低、早产更多、低出生体重和小于胎龄儿更多。重度病例的剖宫产率以及入住新生儿重症或中级护理病房的人数更高。当分析排除早产妊娠时,也发现了类似趋势。总之,在这一特定的厄瓜多尔低收入人群中,合并重度子痫前期/子痫的妊娠围产期结局不良。

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