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已发表的血流导向闭塞量表的评分者间信度。

Inter-rater reliability of published flow diversion occlusion scales.

作者信息

Mazur Marcus D, Taussky Philipp, Shah Lubdha M, Winegar Blair, Park Min S

机构信息

Department of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.

Department of Neuroradiology, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA.

出版信息

J Neurointerv Surg. 2016 Dec;8(12):1294-1298. doi: 10.1136/neurintsurg-2015-012193. Epub 2016 Jan 20.

Abstract

BACKGROUND

With increasing use of flow-diverting stents for the treatment of intracranial aneurysms, standardized methods and a common language to evaluate angiographic outcomes are needed. Multiple grading scales have been developed for this purpose but none has been widely adopted.

OBJECTIVE

To analyze these scales to determine interobserver reliability.

METHODS

Four independent assessors scored the intraprocedural angiograms of patients who underwent flow-diverting stent deployment for an intracranial saccular or fusiform aneurysm at our institution between October 2012 and June 2015. Angiographic outcome immediately after flow-diverting stent deployment was scored using three grading scales (Kamran-Byrne (KB), Simple Measurement of Aneurysm Residual after Treatment (SMART), and O'Kelley, Krings, Marotta (OKM)). Statistical analysis was performed using Light's κ for multiple raters (κ), Kendall's coefficient of concordance (W), and intraclass correlation (ICC).

RESULTS

We included the angiograms of 50 consecutive patients (mean age 58 years, range 30-79) who underwent flow-diverting stent deployment for an intracranial aneurysm (40 saccular, 10 fusiform). Six aneurysms were located in the posterior circulation. The inter-rater reliability was typically poor or fair: SMART aneurysm filling (κ=0.30, W=0.36, ICC=0.12), SMART parent vessel stenosis (κ=0.07, W=0.33, ICC=0.12), KB axis I (κ=0.24, W=0.50, ICC=0.25), KB axis II (κ=0.07, W=0.30, ICC=0.06), OKM aneurysm filling (κ=0.23, W=0.45, ICC=0.13), OKM contrast stasis (κ=0.36,W=0.71, ICC=0.54).

CONCLUSIONS

Existing flow-diverting stent grading scales have low inter-rater reliability for most categories.

摘要

背景

随着血流导向支架在颅内动脉瘤治疗中的应用日益增多,需要标准化的方法和通用语言来评估血管造影结果。为此已开发了多种分级量表,但均未被广泛采用。

目的

分析这些量表以确定观察者间的可靠性。

方法

4名独立评估者对2012年10月至2015年6月间在本机构接受血流导向支架置入治疗颅内囊状或梭形动脉瘤患者的术中血管造影进行评分。使用三种分级量表(Kamran-Byrne(KB)、治疗后动脉瘤残余简单测量(SMART)和O'Kelley、Krings、Marotta(OKM))对血流导向支架置入后立即的血管造影结果进行评分。使用针对多个评分者的Light's κ(κ)、肯德尔和谐系数(W)和组内相关系数(ICC)进行统计分析。

结果

我们纳入了50例连续接受颅内动脉瘤血流导向支架置入的患者(平均年龄58岁,范围30-79岁)的血管造影(40例囊状,10例梭形)。6个动脉瘤位于后循环。观察者间可靠性通常较差或一般:SMART动脉瘤充盈(κ=0.30,W=0.36,ICC=0.12),SMART载瘤血管狭窄(κ=0.07,W=0.33,ICC=0.12),KB轴I(κ=0.24,W=0.50,ICC=0.25),KB轴II(κ=0.07,W=0.30,ICC=0.06),OKM动脉瘤充盈(κ=0.23,W=0.45,ICC=0.13),OKM造影剂滞留(κ=0.36,W=0.71,ICC=0.54)。

结论

现有的血流导向支架分级量表在大多数类别中观察者间可靠性较低。

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