Marker David R, U-Thainual Paweena, Ungi Tamas, Flammang Aaron J, Fichtinger Gabor, Iordachita Iulian I, Carrino John A, Fritz Jan
Russell H. Morgan Department of Radiology and Radiological Science, Musculoskeletal Radiology, Johns Hopkins University School of Medicine, 601 North Caroline Street, JHOC 3140A, Baltimore, MD, 21287, USA.
Department of Mechanical and Materials Engineering, Queen's University, 99 University Avenue, Kingston, ON, Canada.
Skeletal Radiol. 2016 May;45(5):591-7. doi: 10.1007/s00256-016-2333-7. Epub 2016 Jan 20.
Perineural ganglion impar injections are used in the management of pelvic pain syndromes; however, there is no consensus regarding the optimal image guidance. Magnetic resonance imaging (MRI) provides high soft tissue contrast and the potential to directly visualize and target the ganglion. The purpose of this study was to assess the feasibility of MR-guided percutaneous perineural ganglion impar injections.
Six MR-guided ganglion impar injections were performed in six human cadavers. Procedures were performed with a clinical 1.5-Tesla MRI system through a far lateral transgluteus approach. Ganglion impar visibility, distance from the sacrococcygeal joint, number of intermittent MRI control steps required to place the needle, target error between the intended and final needle tip location, inadvertent punctures of non-targeted vulnerable structures, injectant distribution, and procedure time were determined.
The ganglion impar was seen on MRI in 4/6 (66 %) of cases and located 0.8 mm cephalad to 16.3 mm caudad (average 1.2 mm caudad) to the midpoint of the sacrococcygeal joint. Needle placement required an average of three MRI control steps (range, 2-6). The average target error was 2.2 ± 2.1 mm. In 6/6 cases (100 %), there was appropriate periganglionic distribution and filling of the presacrococcygeal space. No punctures of non-targeted structures occurred. The median procedure time was 20 min (range, 12-29 min).
Interventional MRI can visualize and directly target the ganglion impar for accurate needle placement and successful periganglionic injection with the additional benefit of no ionizing radiation exposure to patient and staff. Our results support clinical evaluation.
阴部神经奇神经节注射用于骨盆疼痛综合征的治疗;然而,关于最佳影像引导方式尚无共识。磁共振成像(MRI)提供了高软组织对比度,并且有直接可视化并靶向该神经节的潜力。本研究的目的是评估磁共振引导下经皮阴部神经奇神经节注射的可行性。
在6具人体尸体上进行了6次磁共振引导下的奇神经节注射。操作通过远外侧经臀肌入路,使用临床1.5特斯拉MRI系统进行。确定奇神经节的可视性、与骶尾关节的距离、放置针头所需的间歇性MRI控制步骤数量、预期针尖位置与最终针尖位置之间的靶点误差、非靶向易损结构的意外穿刺、注射剂分布和操作时间。
6例中有4例(66%)在MRI上可见奇神经节,其位于骶尾关节中点头侧0.8毫米至尾侧16.3毫米(平均尾侧1.2毫米)处。针头放置平均需要3次MRI控制步骤(范围为2 - 6次)。平均靶点误差为2.2±2.1毫米。6例(100%)均出现节前间隙的适当分布和填充。未发生非靶向结构的穿刺。中位操作时间为20分钟(范围为12 - 29分钟)。
介入性MRI可以可视化并直接靶向奇神经节,以实现准确的针头放置和成功的节前注射,此外还能使患者和工作人员免受电离辐射。我们的结果支持进行临床评估。