Kucherov Victor, Hulbert William, Wu Guan
Department of Urology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Urol Case Rep. 2015 Mar 2;3(3):72-3. doi: 10.1016/j.eucr.2015.01.010. eCollection 2015 May.
Two males ages 16 and 23 years presented with new testicular pain while taking minocycline. Both patients experienced resolution of their symptoms only after minocycline discontinuation. Testicular pain with minocycline use has been previously described, however only in the setting of systemic autoimmune reactions (which were absent here). These cases represent probable rare adverse reactions to minocycline. For patients taking minocycline who experience otherwise unexplained testicular pain, a trial discontinuation of this medication should be considered.
两名年龄分别为16岁和23岁的男性在服用米诺环素时出现了新的睾丸疼痛。两名患者均仅在停用米诺环素后症状才得以缓解。此前已有关于使用米诺环素导致睾丸疼痛的描述,但仅出现在全身性自身免疫反应的情况下(此处不存在这种情况)。这些病例代表了米诺环素可能罕见的不良反应。对于服用米诺环素且出现无法解释的睾丸疼痛的患者,应考虑试验性停用该药物。