HIV感染中的急性肾损伤
Acute Kidney Injury in HIV Infection.
作者信息
Li Xuezhu, Zhuang Shougang
机构信息
Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Department of Nephrology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China; Department of Medicine, Rhode Island Hospital and Alpert Medical School of Brown University, USA.
出版信息
J Trop Dis. 2013 Apr;1(1). doi: 10.4172/2329-891X.1000101. Epub 2013 Feb 25.
Acute kidney injury (AKI) is increasingly recognized in clinical practice, and common in HIV-infection patients, affecting 18% of hospitalized patients. Preexisting hypertension, advanced HIV-infection, tenofovir toxicity, HCV co-infection, sepsis are risk factors of AKI. AKI can lead to prolonged hospitalization and is associated with increased mortality in HIV-infected patients. This review provides the most recent updates in the definition, diagnosis, pathophysiology, risk factors and treatment options for patients with HIV-associated AKI.
急性肾损伤（AKI）在临床实践中越来越受到重视，在HIV感染患者中很常见，影响18%的住院患者。既往高血压、晚期HIV感染、替诺福韦毒性、丙型肝炎病毒合并感染、脓毒症是AKI的危险因素。AKI可导致住院时间延长，并与HIV感染患者死亡率增加相关。本综述提供了HIV相关AKI患者在定义、诊断、病理生理学、危险因素和治疗选择方面的最新进展。
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