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一名7个月大男孩的吉兰-巴雷综合征成功应用血浆置换疗法。

Guillain-Barre syndrome in a 7-month-old boy successfully applied plasma exchange.

作者信息

Akarcan Sanem Eren, İşgüder Rana, Yılmaz Ünsal, Ayhan Yüce, Ceylan Gökhan, Ağın Hasan

机构信息

Pediatric Intensive Care Unit, Dr. Behçet Uz Children's Training and Research Hospital, İzmir, Turkey.

Pediatric Intensive Care Unit, Dr. Behçet Uz Children's Training and Research Hospital, İzmir, Turkey.

出版信息

Transfus Apher Sci. 2016 Feb;54(1):139-43. doi: 10.1016/j.transci.2016.01.001. Epub 2016 Jan 12.

Abstract

Despite being the most common cause of acute flaccid paralysis in children Guillain-Barré syndrome has a low incidence under 18 years old, and is even rarer under the age of 2. Established treatment regimens include intravenous immunoglobulin and plasma exchange in older children and adults. However very limited data are available for the efficacy and safety of plasma exchange in infants younger than 12 month-old. This article presents the experience of plasma exchange in the case of 7-month-old boy diagnosed with Guillain-Barré syndrome. A 7-month-old boy was referred to the pediatric intensive care unit with a 10-day history of progressive weakness, feeding difficulty and constipation. He was diagnosed with axonal Guillain-Barré syndrome on the basis of clinical and electromyographical findings. The patient recovered fully with intravenous immunoglobulin and plasma exchange. Plasma exchange may be a safe option in the treatment in infants with Guillain-Barré syndrome as young as 7-month-age.

摘要

尽管格林-巴利综合征是儿童急性弛缓性麻痹最常见的病因,但在18岁以下发病率较低,在2岁以下更为罕见。既定的治疗方案包括对大龄儿童和成人进行静脉注射免疫球蛋白和血浆置换。然而,关于12个月以下婴儿血浆置换的疗效和安全性的数据非常有限。本文介绍了一名7个月大被诊断为格林-巴利综合征男孩的血浆置换经验。一名7个月大的男孩因进行性肌无力、喂养困难和便秘10天被转诊至儿科重症监护病房。根据临床和肌电图检查结果,他被诊断为轴索性格林-巴利综合征。该患者通过静脉注射免疫球蛋白和血浆置换完全康复。血浆置换对于年仅7个月大的格林-巴利综合征婴儿可能是一种安全的治疗选择。

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