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中国精神分裂症患者的生活质量、感知耻辱感与药物依从性比较:一项随访研究。

Comparison of the Quality of Life, Perceived Stigma and Medication Adherence of Chinese with Schizophrenia: A Follow-Up Study.

作者信息

Wang Xiao-Qin, Petrini Marcia, Morisky Donald E

机构信息

HOPE School of Nursing, Wuhan University, Wuhan, P.R. China.

HOPE School of Nursing, Wuhan University, Wuhan, P.R. China.

出版信息

Arch Psychiatr Nurs. 2016 Feb;30(1):41-6. doi: 10.1016/j.apnu.2015.10.006. Epub 2015 Oct 21.

Abstract

OBJECTIVES

The community-based mental health services were encouraged to improve the quality of life for individuals with chronic mental disorders in Mainland China. This study aims to explore how the quality of life, perceived stigma, and medication adherence differ among a Chinese population with schizophrenia prior to and one-month following discharge.

METHOD

One hundred and twenty-eight Chinese people with schizophrenia completed the self-report scales: the Schizophrenia Quality of Life Scale (SQLS), the Link' Stigma Scale, and the Morisky Medication Adherence Scale (MMAS-8) prior to discharge and at one month after discharge. Data were analyzed using descriptive statistics and a paired sample t-test.

RESULTS

The findings of SQLS demonstrate deterioration on psychosocial and motivation/energy domain (P<0.001) accompanied by improvement of symptom/side effect (P<0.05) after discharge. The scores of perceived stigma and actual stigma coping orientations (P<0.001) after discharge were found to be significantly higher than before discharge. Medication adherence was significantly reduced after discharge than before discharge (P<0.001).

CONCLUSION

The results of this study provide implications for clinical practices, such as provision of psychosocial and educational rehabilitation programs for individuals who are in a stable mental status and plan to discharge; and to provide effective family education in order to improve family coping strategies and caring capabilities when patients return to the community. The findings provide important policy implications as well to facilitate individuals with schizophrenia to reintegrate into the community and benefit from a favorable QOL.

摘要

目的

鼓励中国大陆基于社区的心理健康服务改善慢性精神障碍患者的生活质量。本研究旨在探讨中国精神分裂症患者出院前和出院后一个月在生活质量、感知耻辱感和药物依从性方面的差异。

方法

128名中国精神分裂症患者在出院前和出院后一个月完成了自我报告量表:精神分裂症生活质量量表(SQLS)、林氏耻辱感量表和莫利斯基药物依从性量表(MMAS-8)。使用描述性统计和配对样本t检验对数据进行分析。

结果

SQLS的结果显示,出院后心理社会和动机/能量领域恶化(P<0.001),同时症状/副作用有所改善(P<0.05)。出院后感知耻辱感和实际耻辱应对取向的得分(P<0.001)显著高于出院前。出院后药物依从性显著低于出院前(P<0.001)。

结论

本研究结果对临床实践具有启示意义,例如为精神状态稳定且计划出院的个体提供心理社会和教育康复项目;并提供有效的家庭教育,以提高患者回归社区时家庭的应对策略和照顾能力。这些发现也为促进精神分裂症患者重新融入社区并从良好的生活质量中受益提供了重要的政策启示。

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