Dwivedi M, Acharya S K, Nundy S, Tandon B N
Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi.
Gastroenterol Jpn. 1989 Oct;24(5):573-9. doi: 10.1007/BF02773888.
The diagnostic accuracy of ultrasonography (US) was evaluated in delineating the site and cause of biliary obstruction in 59 patients of surgical obstructive jaundice (SOJ). A final analysis of the ultrasonographic data was carried out in 42 patients on whom laparotomy or endoscopic papillotomy with removal of common bile duct stones, confirmed the diagnosis. Evaluation of the role of second investigation following ultrasound in 28 patients (side-viewing endoscopy in 13, ERCP in 12 and PTC in 3) was also done to determine whether they provide any additional information over ultrasonography in delineating the exact level and etiology of biliary obstruction. US was done by the clinician who interpreted the findings in conjunction with the clinical profile of the patient. US correctly diagnosed SOJ in all 42 patients. In 26 of the 28 patients with distal CBD block (specificity 87.5%; sensitivity 100%) and in 14 out of 16 patients with proximal CBD block (specificity 100%; sensitivity 87.5%) US provided and accurate diagnosis of the site of obstruction. US was correct in diagnosing a malignant etiology in 26 out of 27 malignant cases whereas it accurately indentified the benign nature of biliary obstruction in 14 of the 15 patients of SOJ due to benign obstruction (specificity and sensitivity range 93.3% to 96.3%). A second investigation could correctly change the etiology and site of biliary obstruction in only 5 patients (17.9%) whereas in the remaining 23 patients (82.1%) it did not add any additional information over the US findings. Six out of fifteen patients (40%) who underwent cholangiography had cholangitis and in one severe septicemia led to death.(ABSTRACT TRUNCATED AT 250 WORDS)
对59例外科梗阻性黄疸(SOJ)患者,评估超声检查(US)在明确胆道梗阻部位及病因方面的诊断准确性。对42例接受剖腹手术或内镜乳头切开取胆总管结石并确诊的患者进行了超声数据的最终分析。还对28例患者(13例行侧视内镜检查、12例行内镜逆行胰胆管造影术(ERCP)、3例行经皮肝穿刺胆管造影术(PTC))进行了超声检查后二次检查作用的评估,以确定在明确胆道梗阻确切部位和病因方面,二次检查是否能提供比超声检查更多的信息。超声检查由临床医生进行,他们结合患者的临床情况解读检查结果。超声检查在所有42例患者中均正确诊断出SOJ。在28例胆总管远端梗阻患者中的26例(特异性87.5%;敏感性100%)以及16例胆总管近端梗阻患者中的14例(特异性100%;敏感性87.5%)中,超声检查准确诊断出了梗阻部位。超声检查在27例恶性病例中的26例中正确诊断出恶性病因,而在15例因良性梗阻导致的SOJ患者中的14例中准确识别出胆道梗阻的良性性质(特异性和敏感性范围为93.3%至96.3%)。二次检查仅能在5例患者(17.9%)中正确改变胆道梗阻的病因和部位,而在其余23例患者(82.1%)中,二次检查并未提供比超声检查结果更多的信息。15例行胆管造影的患者中有6例(40%)发生胆管炎,其中1例因严重败血症死亡。(摘要截短至250字)