Hu JunMei, Bortsov Andrey V, Ballina Lauren, Orrey Danielle C, Swor Robert A, Peak David, Jones Jeffrey, Rathlev Niels, Lee David C, Domeier Robert, Hendry Phyllis, Parry Blair A, McLean Samuel A
TRYUMPH Research Program, University of North Carolina, Chapel Hill, NC, USA Anesthesiology, University of North Carolina, Chapel Hill, NC, USA Emergency Medicine, William Beaumont Hospital, Royal Oak, MI, USA Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA Emergency Medicine, Spectrum Health System, Grand Rapids, MI, USA Emergency Medicine, Baystate Medical Center, Springfield, MA, USA Emergency Medicine, North Shore University Hospital, Manhasset, NY, USA Emergency Medicine, Saint Joseph Mercy Health System, Ypsilanti, MI, USA Emergency Medicine, University of Florida, Jacksonville, FL, USA Emergency Medicine, University of North Carolina, Chapel Hill, NC, USA.
Pain. 2016 Feb;157(2):438-444. doi: 10.1097/j.pain.0000000000000388.
Motor vehicle collision (MVC) can trigger chronic widespread pain (CWP) development in vulnerable individuals. Whether such CWP typically develops through the evolution of pain from regional to widespread or through the early development of widespread pain with nonrecovery is currently unknown. We evaluated the trajectory of CWP development (American College of Rheumatology criteria) among 948 European-American individuals who presented to the emergency department (ED) for care in the early aftermath of MVC. Pain extent was assessed in the ED and 6 weeks, 6 months, and 1 year after MVC on 100%, 91%, 89%, and 91% of participants, respectively. Individuals who reported prior CWP at the time of ED evaluation (n = 53) were excluded. Trajectory modeling identified a 2-group solution as optimal, with the Bayes Factor value (138) indicating strong model selection. Linear solution plots supported a nonrecovery model. Although the number of body regions with pain in the non-CWP group steadily declined, the number of body regions with pain in the CWP trajectory group (192/895, 22%) remained relatively constant over time. These data support the hypothesis that individuals who develop CWP after MVC develop widespread pain in the early aftermath of MVC, which does not remit.
机动车碰撞(MVC)可促使易患个体发生慢性广泛性疼痛(CWP)。目前尚不清楚这种CWP通常是通过疼痛从局部发展为广泛性演变而来,还是通过广泛性疼痛早期发作且未恢复而发展形成。我们评估了948名在MVC后早期到急诊科(ED)就诊的欧美个体中CWP的发展轨迹(美国风湿病学会标准)。分别在MVC后的急诊科以及6周、6个月和1年时对100%、91%、89%和91%的参与者进行了疼痛范围评估。在ED评估时报告有既往CWP的个体(n = 53)被排除。轨迹模型确定两组解决方案为最佳,贝叶斯因子值(138)表明模型选择有力。线性解决方案图支持非恢复模型。尽管非CWP组疼痛的身体区域数量稳步下降,但CWP轨迹组(192/895,22%)疼痛的身体区域数量随时间保持相对恒定。这些数据支持以下假设:MVC后发生CWP的个体在MVC后早期即出现广泛性疼痛,且这种疼痛不会缓解。