Sumiyoshi Tetsuya, Kondo Tomohiro, Fujii Ryoji, Minagawa Takeyoshi, Fujie Shinya, Kimura Tomohiro, Ihara Hideyuki, Yoshizaki Naohito, Kondo Hitoshi, Kitayama Hiromitsu, Sugiyama Junko, Hirayama Michiaki, Tsuji Yasushi, Yamamoto Kazuyuki, Kawarada You, Okushiba Shunichi, Nishioka Noriko, Shimizu Tadashi
Dept. of Gastroenterology, Tonan Hospital.
Gan To Kagaku Ryoho. 2015 Dec;42(13):2497-500.
A 74-year-old woman with advanced gastric cancer was admitted to our hospital. A central venous (CV) port catheter was implanted into the right subclavian vein for preoperative chemotherapy and parenteral nutritional management. On the 35th day after implantation, she complained of diarrhea, fever and dyspnea. The chest radiograph showed a right-sided massive pleural effusion. As the patient progressively fell into severe respiratory distress, endotracheal intubation was performed for management of respiration by mechanical ventilation. Initially, given the patient's symptoms, she was diagnosed with septic shock. Therefore, after placement of a CV catheter through the right femoral vein, in consideration of the possibility of a port infection, she was treated with thoracentesis and infusion of antibiotics. The patient gradually recovered, and again received parenteral nutrition through the CV port catheter. After the infusion was administered, she complained of dyspnea. A CT scan of the chest revealed a right pleural effusion and displacement of the tip of the CV port catheter out of the wall of the superior vena cava. We diagnosed delayed vascular injury (DVI), and the CV port catheter was removed. She soon recovered with conservative treatment. We speculated that the initial respiratory symptoms such as the pleural effusion were caused by DVI. DVI should therefore be recognized as a complication related to implanted CV port catheters.
一名74岁的晚期胃癌女性患者入住我院。为进行术前化疗和肠外营养管理,在其右锁骨下静脉植入了中心静脉(CV)端口导管。植入后第35天,她出现腹泻、发热和呼吸困难。胸部X线片显示右侧大量胸腔积液。随着患者逐渐陷入严重呼吸窘迫,遂行气管插管以进行机械通气管理呼吸。最初,鉴于患者症状,诊断为感染性休克。因此,在通过右股静脉置入CV导管后,考虑到端口感染的可能性,对她进行了胸腔穿刺和抗生素输注治疗。患者逐渐康复,并再次通过CV端口导管接受肠外营养。输注后,她诉说呼吸困难。胸部CT扫描显示右侧胸腔积液以及CV端口导管尖端移出上腔静脉壁。我们诊断为迟发性血管损伤(DVI),并移除了CV端口导管。经保守治疗她很快康复。我们推测最初的呼吸症状如胸腔积液是由DVI引起的。因此,DVI应被视为与植入的CV端口导管相关的一种并发症。