Profile of Lawrence Steinman.
作者信息
Davis Tinsley
出版信息
Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1468-70. doi: 10.1073/pnas.1600083113. Epub 2016 Jan 25.
Abstract
摘要
相似文献
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本文引用的文献
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Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease.淀粉样原纤维激活B-1a淋巴细胞以改善炎症性脑病。
Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15016-23. doi: 10.1073/pnas.1521206112. Epub 2015 Nov 30.
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The road not taken: antigen-specific therapy and neuroinflammatory disease.
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Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.质粒编码的胰岛素原在保留 C 肽的同时，特异性减少 1 型糖尿病中胰岛素原特异性 CD8⁺ T 细胞。
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Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.由六聚体肽组成的淀粉样纤维可减轻神经炎症。
Sci Transl Med. 2013 Apr 3;5(179):179ra42. doi: 10.1126/scitranslmed.3005681.
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Natalizumab: bench to bedside and beyond.那他珠单抗：从实验室到临床应用及更多。
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Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.经外周给予β-淀粉样蛋白可逆转实验性自身免疫性脑脊髓炎的 TH1 和 TH17 型的瘫痪和炎症反应。
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Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation.鉴定髓鞘中具有缓解神经炎症作用的天然脂肪酸。
Sci Transl Med. 2012 Jun 6;4(137):137ra73. doi: 10.1126/scitranslmed.3003831.
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Atomic view of a toxic amyloid small oligomer.有毒淀粉样小寡聚物的原子视角。
Science. 2012 Mar 9;335(6073):1228-31. doi: 10.1126/science.1213151.
9
Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.对活动性多发性硬化症病灶的蛋白质组学分析揭示了治疗靶点。
Nature. 2008 Feb 28;451(7182):1076-81. doi: 10.1038/nature06559. Epub 2008 Feb 17.
10
Treatment of multiple sclerosis with the monoclonal anti-CD4 antibody cM-T412: results of a randomized, double-blind, placebo-controlled, MR-monitored phase II trial.使用单克隆抗CD4抗体cM-T412治疗多发性硬化症：一项随机、双盲、安慰剂对照、磁共振监测的II期试验结果
Neurology. 1997 Aug;49(2):351-7. doi: 10.1212/wnl.49.2.351.
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