Wang Shigang, Ma Ren, Zhang Shunqi, Yin Tao, Liu Zhipeng
Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300192, China.
College of Radiology, Taishan Medical University, Taian, 271016, China.
Biomed Eng Online. 2016 Jan 27;15:10. doi: 10.1186/s12938-016-0125-x.
Magneto-acoustic tomography with current injection involves using electrical impedance imaging technology. To explore the potential applications in imaging biological tissue and enhance image quality, a new scan mode for the transducer is proposed that is based on translational and circular scanning to record acoustic signals from sources.
An imaging algorithm to analyze these signals is developed in respect to this alternative scanning scheme. Numerical simulations and physical experiments were conducted to evaluate the effectiveness of this scheme. An experiment using a graphite sheet as a tissue-mimicking phantom medium was conducted to verify simulation results. A pulsed voltage signal was applied across the sample, and acoustic signals were recorded as the transducer performed stepped translational or circular scans. The imaging algorithm was used to obtain an acoustic-source image based on the signals.
In simulations, the acoustic-source image is correlated with the conductivity at the sample boundaries of the sample, but image results change depending on distance and angular aspect of the transducer. In general, as angle and distance decreases, the image quality improves. Moreover, experimental data confirmed the correlation.
The acoustic-source images resulting from the alternative scanning mode has yielded the outline of a phantom medium. This scan mode enables improvements to be made in the sensitivity of the detecting unit and a change to a transducer array that would improve the efficiency and accuracy of acoustic-source images.
电流注入式磁声断层成像涉及使用电阻抗成像技术。为了探索其在生物组织成像中的潜在应用并提高图像质量,提出了一种基于平移和圆周扫描的换能器新扫描模式,用于记录来自声源的声学信号。
针对这种替代扫描方案开发了一种分析这些信号的成像算法。进行了数值模拟和物理实验以评估该方案的有效性。使用石墨片作为组织模拟体模介质进行了实验以验证模拟结果。在样品上施加脉冲电压信号,并在换能器进行步进平移或圆周扫描时记录声学信号。使用成像算法根据这些信号获得声源图像。
在模拟中,声源图像与样品边界处的电导率相关,但图像结果会根据换能器的距离和角度方向而变化。一般来说,随着角度和距离减小,图像质量提高。此外,实验数据证实了这种相关性。
替代扫描模式产生的声源图像给出了体模介质的轮廓。这种扫描模式能够提高检测单元的灵敏度,并改变换能器阵列,从而提高声源图像的效率和准确性。