Frongia G, Mehrabi A, Ziebell L, Schenk J P, Günther P
a Division of Pediatric Surgery, Department of General , Visceral and Transplantation Surgery.
b Department of General , Visceral and Transplantation Surgery.
J Invest Surg. 2016 Aug;29(4):185-94. doi: 10.3109/08941939.2015.1114690. Epub 2016 Jan 29.
Assessment of risk factors for postoperative complications following surgical treatment of pediatric perforated appendicitis (PA) is necessary to identify those patients in need of closer monitoring. In this study, we have investigated the impact of different risk factors on the occurrence of complications after an appendectomy in children with PA.
The study was a retrospective, single-centre analysis of all pediatric PA conducted over a 10-year period. Preoperative clinical and laboratory results, intraoperative findings, and postoperative complications were analyzed. Risk factors were defined and a risk score was determined for postoperative complications and reinterventions.
Surgical treatment for appendicitis was performed in 840 pediatric patients during the observation period. 163 of the included patients were diagnosed with PA (mean age 8.9 ± 3.6 years). 19 (11.7%) patients developed postoperative complications, 17 (10.4%) of which required complication-related intervention. We identified five predictors of postoperative complications: the C-related protein value at admission, purulent peritonitis, open appendectomy (primary, secondary, or converted), placement of an abdominal drain, and administration of antibiotics not compliant to results from the subsequent antibiogram. The determined risk score was significantly higher in the complication group (p < .0001) and reintervention group (p < .001).
Postoperative complications following pediatric PA can be predicted using specific preoperative, intraoperative, and postoperative risk factors. In the high-risk group, an active prevention, detection, and intervention of any occurring complication is necessary and we present a new specific pediatric risk score to define patients at risk for complications.
评估小儿穿孔性阑尾炎(PA)手术治疗后术后并发症的危险因素,对于确定那些需要密切监测的患者很有必要。在本研究中,我们调查了不同危险因素对PA患儿阑尾切除术后并发症发生情况的影响。
本研究是对10年间所有小儿PA病例进行的回顾性单中心分析。分析了术前临床和实验室检查结果、术中发现以及术后并发症。定义了危险因素,并确定了术后并发症和再次干预的风险评分。
在观察期内,对840例小儿患者进行了阑尾炎手术治疗。其中163例患者被诊断为PA(平均年龄8.9±3.6岁)。19例(11.7%)患者出现术后并发症,其中17例(10.4%)需要进行与并发症相关的干预。我们确定了术后并发症的五个预测因素:入院时的C反应蛋白值、化脓性腹膜炎、开放式阑尾切除术(初次、二次或中转)、放置腹腔引流管以及抗生素使用不符合后续药敏试验结果。并发症组(p<.0001)和再次干预组(p<.001)的风险评分明显更高。
小儿PA术后并发症可通过特定的术前、术中和术后危险因素进行预测。在高危组中,积极预防、检测和干预任何出现的并发症是必要的,我们提出了一种新的特定小儿风险评分来定义有并发症风险的患者。