Mizuguchi Yoshiaki, Matsumoto Satoshi, Kan Hayato, Koizumi Michihiro, Kuriyama Shou, Uchida Eiji
Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School.
J Nippon Med Sch. 2015;82(6):290-4. doi: 10.1272/jnms.82.290.
Necrotizing fasciitis (NF) is an aggressive soft tissue infection that involves the deep fascia and is characterized by the extensive deterioration of the surrounding tissue. Immediate recognition and aggressive treatment, including debridement and systemic antibiotics, are mandatory for the successful management of NF. Following radical debridement, closure of the remaining wound can pose significant reconstructive challenges. Accumulating evidence indicates that application of negative-pressure wound therapy (NPWT) is useful in the treatment of patients with severe acute complex wounds, including NF.
A 58-year-old man who had undergone surgical resection for rectal carcinoma followed by chemo-radiation therapy developed NF of the pelvis and thigh three years after the surgical procedure. Following extensive debridement, a VAC system was applied to the large open wound and successfully contributed to wound bed cleansing, which was followed by surgery for skin grafting.
This case demonstrates the successful management of a complex and potentially lethal wound of the perineum to lower leg with debridement and skin grafting as well as with the application of the VAC system.
坏死性筋膜炎(NF)是一种侵袭性软组织感染,累及深筋膜,其特征是周围组织广泛恶化。对于NF的成功治疗,必须立即识别并积极治疗,包括清创和全身使用抗生素。在进行根治性清创后,闭合剩余伤口可能会带来重大的重建挑战。越来越多的证据表明,负压伤口治疗(NPWT)在治疗包括NF在内的严重急性复杂伤口患者中是有用的。
一名58岁男性,因直肠癌接受手术切除,随后进行放化疗,术后三年出现骨盆和大腿的NF。在进行广泛清创后,将VAC系统应用于大的开放性伤口,成功地促进了伤口床的清洁,随后进行了皮肤移植手术。
本病例展示了通过清创、皮肤移植以及应用VAC系统成功处理了从会阴到小腿的复杂且可能致命的伤口。