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99mTc-甲氧基异丁基异腈 SPECT/CT 显像的 1 型多发性内分泌腺瘤病患者的垂体泌乳素瘤。

Pituitary Prolactinoma Imaged by 99mTc-Sestamibi SPECT/CT in a Multiple Endocrine Neoplasia Type 1 Patient.

机构信息

From the Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

出版信息

Clin Nucl Med. 2016 Jun;41(6):497-9. doi: 10.1097/RLU.0000000000001144.

Abstract

A 35-year-old woman who had undergone bilateral inferior parathyroidectomy for primary hyperparathyroidism was referred to our hospital to evaluate the cause of irregular menses, galactorrhea, and paroxysmal headache. Multiple endocrine neoplasia type 1 was then suspected for the high levels of plasma prolactin, parathyroid hormone, serum calcium, insulin, and related symptoms. A Tc-sestamibi SPECT/CT acquired to evaluate parathyroid glands unexpectedly revealed an increased accumulation in the pituitary gland, which was further confirmed by enhanced magnetic resonance imaging as a pituitary microadenoma. Bromocriptine treatment gradually reduced the prolactin level.

摘要

一位 35 岁女性因原发性甲状旁腺功能亢进症接受了双侧甲状旁腺切除术,因月经不规律、溢乳和阵发性头痛而被转至我院。考虑到患者血浆催乳素、甲状旁腺激素、血清钙、胰岛素水平升高以及相关症状,怀疑其患有多发性内分泌腺瘤病 1 型。为评估甲状旁腺,我们对患者进行了 Tc-sestamibi SPECT/CT 检查,结果显示,患者的垂体有异常浓聚,进一步的增强磁共振成像证实为垂体微腺瘤。溴隐亭治疗逐渐降低了催乳素水平。

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