Olejnik P, Tittel P, Venczelova Z, Masura J
Bratisl Lek Listy. 2016;117(2):72-6. doi: 10.4149/bll_2016_014.
To present our experience with stent implantations in non-surgically treated patients with pulmonary atresia, ventricular septal defect and stenotic aortopulmonary collaterals.
Between April 2007 and June 2009, 6 stents in 4 patients were implanted into stenosed segments of MAPCAs. The median age and weight of patients at stent implantation were 24 years (range 13-34 years) and 58.5 kg (range 56-70 kg), respectively.
All implantations were successfully performed; there were no procedure associated complications. The median diameter increase of stenosed MAPCAs was 107%. The mean arterial blood saturation increased from mean 78% to 84%. An early increase in the median exercise duration measured by 6MWT was 36%. Neointimal in-stent fibroproliferation in 4/6 stents and stent fracture in 1/6 patients occured in mid-term follow-up.
Percutaneous catheterizational stent implantation into stenosed segments of MAPCAs is a palliative procedure, that might improve quality of life of non-surgically treated patients with PA, VSD, MAPCAs. Neointimal in-stent fibroproliferation and stent fracture can be expected as complications in mid-term follow-up. CT-angiography is recommended to confirm these complications in progressive satO2 decrease (Fig. 3, Ref. 12).
介绍我们对非手术治疗的肺动脉闭锁、室间隔缺损和狭窄性主肺动脉侧支患者进行支架植入的经验。
2007年4月至2009年6月,对4例患者的6个支架植入到主肺动脉侧支狭窄段。支架植入时患者的中位年龄和体重分别为24岁(范围13 - 34岁)和58.5千克(范围56 - 70千克)。
所有植入均成功完成;无手术相关并发症。狭窄的主肺动脉侧支的中位直径增加了107%。动脉血氧饱和度平均值从78%升至84%。通过6分钟步行试验测量的中位运动持续时间早期增加了36%。中期随访中,6个支架中有4个出现支架内新生内膜纤维增生,6例患者中有1例出现支架断裂。
经皮导管将支架植入主肺动脉侧支狭窄段是一种姑息性手术,可能改善非手术治疗的肺动脉闭锁、室间隔缺损、主肺动脉侧支患者的生活质量。中期随访中可预期支架内新生内膜纤维增生和支架断裂为并发症。建议行CT血管造影以证实进行性血氧饱和度降低时的这些并发症(图3,参考文献12)。